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Benzodiazepines: What They Are, Uses, Side Effects & Risks

Authored By:

Cynthia Chacon

Edited By:

Amy Leifeste

Medically
Reviewed By:

Sean O'Neill
MS, LMFT 112879

An image of Karena Mathis, author for gratitude lodge
Authored By:

Karena Mathis

Edited By

Amy Leifeste

Sean O'Neill
Medically Reviewed By

Sean O'Neill
MS, LMFT 112879

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Table of Contents

Benzodiazepine Rehab & What You Need To Know

Benzodiazepine side effects can be aggravating. Benzodiazepines (benzos) are a class of prescription medications indicated to address anxiety, muscle spasms, seizures, and sleep disorders. [1] Medical professionals commonly prescribe them for managing anxiety, seizures, and insomnia. In some instances, benzodiazepines are used off-label to alleviate symptoms related to tics and bipolar disorder. [2]

While taking benzodiazepines short-term is generally considered safe and effective, long-term use can result in the development of tolerance, dependence, and other unwanted side effects of benzodiazepines. If you are taking benzodiazepines and want to know more about them, this guide addresses the following issues:

  • What is benzodiazepine therapy?
  • What are the main side effects of taking benzodiazepines?
  • Can the effects of benzodiazepines be dangerous?
  • Are benzos side effects life-threatening?
  • How to connect with benzo addiction treatment in California.

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What Are Benzodiazepines?

Benzodiazepines are depressant drugs that relieve anxiety, muscle spasms, and seizures. The most common benzodiazepines include Valium, Xanax, Halcion, Ativan, and Klonopin. This Schedule IV drug works by creating a sedative or hypnotic effect by slowing down the body’s central nervous system. This often causes sleepiness and relaxes those who take it. Benzodiazepines are controlled substances and are only legally available through a prescription. While effective when prescribed correctly, these drugs are at high risk for misuse and addiction. Some people abuse the drug by “doctor shopping” and getting their prescriptions from multiple sources, or they buy them illicitly. Abusing benzodiazepines is incredibly risky as overdose can result in breathing issues, coma, and possible death. These are the benzodiazepines most commonly prescribed by U.S. physicians:

  • Xanax (alprazolam): For treating panic disorder, anxiety disorder, and premenstrual dysphoric disorder.
  • Librium (chlordiazepoxide): For treating anxiety disorders and to treat alcohol withdrawal.
  • Klonopin (clonazepam): For treating anxiety, agitation, and seizures.
  • Valium (diazepam): For treating muscle spasms, seizures, and alcohol withdrawal.
  • Ativan (lorazepam): For treating anxiety, seizures, and phobias.
  • Restoril (temazepam): For treating insomnia.
  • Halcion (triazolam): For treating insomnia.

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What are benzodiazepines used for?

Benzodiazepines serve various therapeutic purposes and are commonly prescribed for:

  • Anxiety disorders: Benzodiazepines are effective in providing short-term relief for symptoms of generalized anxiety disorder, panic disorder, and social anxiety disorder.
  • Insomnia: Some benzodiazepines, such as Ativan and Restoril, may be prescribed for short-term treatment of sleep disorders due to their sedative effects.
  • Seizures: Benzodiazepines can help manage certain types of seizures by calming excessive electrical activity in the brain.
  • Muscle spasms: Conditions causing muscle spasms or stiffness, such as spasticity associated with neurological disorders, may be treated with benzodiazepines.
  • Alcohol withdrawal: Benzodiazepines can be used to treat alcohol withdrawal syndrome, preventing complications such as seizures.

What do benzodiazepines do?

As depressant drugs, benzodiazepines exert their effects by enhancing the activity of a neurotransmitter called GABA (gamma-aminobutyric acid) in the brain. GABA is an inhibitory neurotransmitter that reduces nerve activity, leading to a calming or sedative effect. By binding to specific receptors on nerve cells, taking benzodiazepines enhances the inhibitory action of GABA, resulting in a decrease in the excitability of neurons. This mechanism contributes to the anxiolytic, muscle-relaxant, and anticonvulsant effects associated with benzodiazepines.

Short-Term Effects of Benzodiazepines

Benzodiazepines, often referred to as benzos, are medications that can produce a range of short-term effects when taken. These effects are typically experienced shortly after consuming the medication and can include:

  • Anxiety reduction: Benzodiazepines are mainly prescribed to alleviate anxiety and can provide rapid relief from symptoms of anxiety. They promote relaxation and calmness. [3]
  • Sedation: Benzos have a sedative effect, which means that they can induce drowsiness and promote sleep. This sedation can be helpful for individuals experiencing insomnia or severe anxiety.
  • Muscle relaxation: These medications have muscle relaxant properties, making them useful for conditions involving muscle tension or spasms.
  • Anti-seizure effects: Benzodiazepines are sometimes prescribed to control and prevent seizures, particularly in emergency situations.
  • Euphoria: Some people may experience a sense of euphoria or well-being when taking benzodiazepines, which can contribute to their potential for misuse.

Long-Term Effects of Benzodiazepines

While taking benzodiazepines can provide short-term relief, long-term use can lead to a range of adverse effects, including:

  • Tolerance: Over time, the body can develop a tolerance to the effects of benzodiazepines, meaning that higher doses are required to achieve the same therapeutic results.
  • Dependence: Prolonged use of benzodiazepines can lead to physical and psychological dependence. Individuals may find it challenging to function without the medication. [4]
  • Withdrawal: Discontinuing benzodiazepines after long-term use can result in withdrawal symptoms, such as increased anxiety, insomnia, and even seizures in severe cases.
  • Cognitive impairment: A common long-term benzo side effect involves impaired cognitive functions, including memory and attention.
  • Increased fall risk: Elderly individuals who use benzodiazepines are at a higher risk of falls and fractures due to the medicationsโ€™ sedative effects.

Benzodiazepines Risks

Carefully consider the following risks when taking benzodiazepines. Firstly, benzodiazepines can interact with other medications, potentially causing adverse effects or reducing the effectiveness of other treatments. Prescribing benzodiazepines can impair patients’ memory and cognitive function, potentially affecting daily life and work performance. High doses of benzodiazepines or mixing them with other substances, such as alcohol or opioids, can result in alcohol withdrawal syndrome, opioid withdrawal, or benzodiazepine overdose, which can be life-threatening. [5] The euphoric effects of taking benzodiazepines can lead to misuse and addiction, especially when used recreationally or in higher doses than prescribed. Abruptly stopping benzo use can lead to severe withdrawal, making it essential to taper off the medication under medical supervision. Individuals prescribed benzodiazepine medication should be aware of these potential effects and risks, use them as directed by a healthcare professional, and seek guidance if they have concerns about their use.

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Are Benzodiazepines Addictive?

Benzodiazepines have the potential for addiction, and their use should be carefully monitored. The risk of dependence increases with prolonged use and higher doses. Abruptly discontinuing benzodiazepine use can lead to withdrawal symptoms, including anxiety, insomnia, and seizures. Follow prescribed dosage guidelines and consult with healthcare professionals to manage and taper off benzodiazepine use safely. Additionally, people with a history of substance abuse may be at a higher risk of developing dependence on benzodiazepines. Regular communication with healthcare providers is essential to balance the therapeutic benefits of these medications while minimizing the risk of addiction.

Benzodiazepines Detox

Detoxification from benzodiazepines is the first vital step in the recovery process for those who have become dependent on these medications. Supervised medical detoxification offers the safest and smoothest pathway to withdrawal due to the potential for severe withdrawal.

Medical supervision with tapered reduction in dose

Detoxing from benzodiazepines should be carried out in a medical setting or under the guidance of a healthcare professional. This is essential because withdrawal symptoms can be intense and even life-threatening. In many cases, a gradual tapering of the benzodiazepine dose is recommended rather than abrupt cessation. This helps the body adjust to lower levels of the medication and reduces the severity of withdrawal. [6]

Benzodiazepines withdrawal symptoms

Benzodiazepine withdrawal symptoms can include anxiety, insomnia, tremors, seizures, and hallucinations. These symptoms can vary in intensity depending on factors such as the dosage and length of benzo use.

Duration

The duration of benzodiazepine detox can vary from a few days to several weeks, depending on individual factors. The goal is to manage withdrawal symptoms until the person is safely benzodiazepine-free.

Medications

In some cases, healthcare providers may use other medications to manage withdrawal symptoms and cravings during detox. These medications are typically chosen based on the specific needs of the individual.

Supportive care

Beyond medical treatment, individuals undergoing benzodiazepine detox may benefit from psychological support and counseling to address the underlying issues that led to benzo use and dependence.

Relapse prevention

Detox is only the initial step in treating benzodiazepine dependence. After detox, individuals should engage in comprehensive addiction treatment, including therapy and support groups, to prevent relapse. Reach out to healthcare professionals or addiction treatment centers for guidance and support. Attempting to detox from benzodiazepines without proper medical supervision can be dangerous, and professional help increases the likelihood of a safe and successful detoxification process.

 Benzodiazepines | FAQs

What is a benzo?

A benzo (benzodiazepine) is a prescription medication and Schedule IV controlled substance in the United States.

What are benzodiazepines used for?

Benzodiazepines uses include the treatment of anxiety, insomnia, muscle spasms, and seizure disorders. They work by enhancing the effects of a neurotransmitter called GABA, which helps calm the central nervous system.

Are there any adverse effects of benzodiazepines?

Yes, there can be adverse effects associated with taking benzodiazepines. Common side effects may include drowsiness, dizziness, and impaired coordination. Prolonged or improper use can lead to more severe adverse effects, including addiction, memory problems, and withdrawal symptoms.

Can you get addicted to benzodiazepines?

Yes, benzodiazepines have a potential for addiction, especially when used for extended periods or in higher doses than prescribed. Developing a physical and psychological dependence on these medications is a significant concern, and abrupt discontinuation can lead to withdrawal symptoms.

Are there any bad side effects of benzodiazepines?

Taking benzodiazepines can indeed have several adverse side effects, including drowsiness, dizziness, blurred vision, and impaired coordination. Additionally, long-term use may result in memory issues, mood swings, and a heightened risk of addiction and withdrawal symptoms when discontinuing the medication.

Is Lexapro a benzodiazepine?

No, Lexapro is not a benzodiazepine. It is an SSRI (selective serotonin reuptake inhibitor) antidepressant.

Is Xanax a benzodiazepine?

Yes, Xanax is a benzodiazepine mainly prescribed to treat panic disorders and anxiety disorders.

Is Zoloft a benzodiazepine?

No, Zoloft is not a benzo. It is an SSRI used to treat depression and anxiety disorders.

Get a Safe, Comfortable Benzo Detox at Gratitude Lodge

If you need help detoxing from benzos, we can help you at Gratitude Lodge in Newport Beach and Long Beach, CA. Our treatment centers are inclusive and pet-friendly, providing you with access to medications to streamline benzo withdrawal and a smooth transition into ongoing inpatient treatment. All Gratitude Lodge treatment programs offer personalized therapy that draws from the following interventions:

When you are ready to detox from benzos and start living free of medication, call 844-576-0144 for immediate assistance.   Sources [1] https://www.dea.gov/factsheets/benzodiazepines [2] https://pubmed.ncbi.nlm.nih.gov/26088120/ [3] https://my.clevelandclinic.org/health/treatments/24570-benzodiazepines-benzos [4] https://www.benzoinfo.com/addiction-vs-physical-dependence/ [5] https://www.bmj.com/content/352/bmj.i90 [6] https://www.pbm.va.gov/PBM/AcademicDetailingService/Documents/Academic_Detailing_Educational_Material_Catalog/59_PTSD_NCPTSD_Provider_Helping_Patients_Taper_BZD.pdf

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