Hydrocodone Detox: Symptoms, Timeline, & Treatment

an image of someone learning about hydrocodone detox

Updated March 28, 2024

Authored By:

Joe Gilmore

Edited By

Amy Leifeste

Medically Reviewed By

Javier Rodriguez-Winter

Authored By:

Joe Gilmore

Edited By

Amy Leifeste

Medically Reviewed By

Javier Rodriguez-Winter

an image of someone learning about hydrocodone detox

Hydrocodone detox is a process during which someone who is dependent on opioids discontinues use. Physical dependence on hydrocodone can develop even in those who use the medication exactly as prescribed by a doctor.

Detoxing hydrocodone is best managed under medical supervision to minimize severe withdrawal symptoms and reduce the likelihood of complications or relapse derailing early recovery. Read on to learn more about the withdrawal symptoms of hydrocodone and discover how to connect with compassionate care.

Hydrocodone Withdrawal Symptoms

Regular use of hydrocodone conditions the body to rely on it for normal functioning, a state known as physical dependence. Dependence is common among individuals addicted to hydrocodone, leading to withdrawal symptoms if the drug’s use is abruptly stopped or dosage reduced. That said, dependence may also develop after the medication is used for legitimate medical purposes.

Withdrawal from hydrocodone can be intensely uncomfortable and challenging to tackle without support. The severity and nature of the symptoms of hydrocodone withdrawal can differ from person to person, often intensifying with prolonged use or higher dosages. Common symptoms of withdrawal from hydrocodone include:

  • Muscle aches
  • Agitation
  • Anxiety
  • Diarrhea, nausea, and vomiting
  • Sleep issues like insomnia
  • Tremors
  • Sweating
  • Elevated body temperature
  • Hydrocodone cravings
  • Goosebumps on skin
  • Abdominal pain
  • Frequent yawning
  • Tearing
  • Restlessness
  • Difficulty focusing
  • Emotional volatility
  • Headaches
  • General lethargy
  • Thoughts of self-harm

Withdrawal includes both physical and psychological dimensions, with mental health symptoms potentially persisting beyond the physical ones. Depression, for instance, is a common psychological withdrawal symptom, compounded by the challenge of deriving pleasure during withdrawal, as opioids significantly alter the brain’s reward mechanisms.

Hydrocodone Withdrawal Timeline

The hydrocodone detox timeline can differ based on the type of hydrocodone formulation you’re using, whether it’s a short-acting variety such as Lortab or Vicodin, or a long-acting version like Hysingla ER or Zohydro ER. That said, withdrawal symptoms typically manifest as follows:

  • Initial phase (12 to 30 hours after the last dose): Symptoms start to present, varying in intensity initially. Short-acting hydrocodone withdrawal symptoms can begin within 12 hours of the last dose and may persist for about 24 hours. Symptoms from long-acting hydrocodone, by contrast, can start within the first 30 hours, extending up to 3 days.
  • Peak phase (1 to 8 days after the last dose): As hydrocodone exits the system and the body struggles to adjust to its absence, symptoms reach their highest intensity. This peak typically occurs during the first 2 days of hydrocodone detox for short-acting formulations and lasts 3 to 5 days, whereas for long-acting hydrocodone, the peak may fall between 3 to 8 days after the last dose, with symptoms possibly extending up to 10 days into detox from hydrocodone.
  • Subsiding phase (3 to 10 days after last dose): During this period, the body gradually adapts to the absence of the drug, and symptoms begin to diminish. For short-acting hydrocodone, this adjustment happens around three to five days after the last dose, and within 10 days for long-acting formulations. Most physical symptoms taper off after this phase, but psychological effects may persist.
  • Long-term phase (weeks to months after the last dose): Some lingering effects like insomnia, depression, and anxiety may persist for weeks or even months. However, withdrawal symptoms from hydrocodone will gradually lessen as the body fully adjusts to life without opioids.

How to Detox from Hydrocodone

Here’s how to detox from hydrocodone safely:

  • Seek medical supervision: Due to the potential for severe withdrawal symptoms, a medically supervised detox is highly recommended. This ensures that any complications can be promptly addressed, and discomfort can be minimized through medications and support.
  • Consider a tapering schedule: Gradually reducing the dose of hydrocodone under a doctor’s supervision can help ease withdrawal symptoms. This method allows the body to adjust slowly to decreasing levels of the opioid.
  • Stay hydrated and nourished: Adequate hydration and nutrition during detox help the body recover and mitigate some withdrawal symptoms like nausea and fatigue.
  • Utilize support systems: Support from healthcare professionals, as well as from friends and family, can provide the encouragement and accountability needed during detox.
  • Explore MAT (medication-assisted treatment): MAT, using medications like buprenorphine or methadone, can help manage cravings and withdrawal symptoms, making the detox process more bearable.
  • Prepare for psychological support: Detox is not just a physical process, but it also has psychological aspects. Counseling or therapy can address the underlying issues related to hydrocodone use and develop coping strategies for the future.
  • Plan for long-term recovery: Detox is the first step in a long journey. Comprehensive addiction treatment, including ongoing therapy and support groups, can help maintain sobriety and prevent relapse.

Detoxing from hydrocodone requires a comprehensive approach that addresses both the physical and psychological aspects of addiction. With the right support and resources, recovery is within reach.

Get Treatment for Hydrocodone Addiction at Gratitude Lodge

Hydrocodone was implicated in the opioid epidemic back in the late 1990s, and the medication continues to be problematic for many people today, despite its legitimate painkilling properties. If you or someone that you care about has been abusing opioids like hydrocodone, we can help you recalibrate your life.

Our medical detox program enables you to withdraw from hydrocodone under close supervision and with access to medications approved by the FDA for treating opioid addiction. After detoxing from hydrocodone, you can transition into ongoing treatment at one of our pet-friendly and inclusive rehabs.

During ongoing inpatient treatment at one of our facilities in Newport Beach or Long Beach, CA, you can engage with individualized treatment plans that may include:

  • Psychotherapies
  • Motivational therapies
  • MAT (medication-assisted treatment)
  • Holistic therapies
  • Group therapy
  • Individual counseling
  • Family therapy
  • Aftercare planning

Call 844-576-0144 today and begin hydrocodone detox right away.

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Jenni Bussi

Jenni Busse MS, LPCC

Jenni Busse MS, LPSS is the Clinical Director at Gratitude Lodge. Jenni oversees the clinical program and the clinical team at Gratitude Lodge as a whole. Jenni has worked in treatment for almost 14 years. Her background as a licensed therapist and her passion for helping others intersected with addiction recovery when she started working primarily in detox residential treatment.
Joe Gilmore

Joseph Gilmore

Joseph Gilmore has been working in the addiction industry for half a decade and has been writing about addiction and substance abuse treatment during that time. He has experience working for facilities all across the country. Connect with Joe on LinkedIn.

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