November 28, 2023

GHB Addiction: Signs, Symptoms, & Treatment

A man leaning on the kitchen counter in deep thought about GHB addiction and treatment

Recognized today as a notorious date rape substance, GHB (gamma hydroxybutyrate) can induce effects ranging from euphoria at low doses to blackouts and amnesia in higher doses. Originally utilized as a surgical anesthetic in the 1960s, this chemical compound later gained infamy as a party drug and fat burner in the 1980s.

If you are concerned about addiction to GHB, read on to learn:

  • How addictive is GHB?
  • What are the main dangers of GHB abuse?
  • What’s the safest approach for GHB detox?
  • What’s the best treatment for GHB overdose?
  • How to get treatment for GHB drug addiction in California.
A woman sitting on the bed in distress, depicting GHB withdrawal symptoms

Is GHB Addictive?

In 2002, the FDA approved Xyrem – a medication containing GHB used for treating narcolepsy – although it is subject to strict regulation as a Schedule III controlled substance.

GHB that is not produced as a pharmaceutical product with FDA approval is categorized as a CNS (central nervous system) depressant. GHB is a Schedule I controlled substance, signifying its strong abuse potential.

Long-term use of GHB can lead to addiction. GHB has a profound influence on the brain, affecting various neurotransmitters, including GABA (gamma-aminobutyric acid). GABA is a chemical messenger that inhibits brain activity, triggering drowsiness and relaxation.

Chronic GHB use can result in dependence, where the brain and body adapt to GHB, requiring its use for normal functioning. Upon discontinuation, those who are dependent on GHB may experience unpleasant withdrawal symptoms. Resultantly, many people continue using GHB to avert withdrawal symptoms, creating a challenging cycle of dependence. These challenges with discontinuation contribute to the cycle of addiction, characterized by persistent engagement in compulsive substance use despite adverse outcomes.

Signs of GHB Addiction

GHB symptoms and signs can vary from person to person, influenced by factors like usage frequency, duration, tolerance, sensitivity, and personal or environmental elements. Common indicators of GHB addiction may include any or all of the following.

Compulsive use

Strong desire to use GHB despite adverse outcomes in various aspects of life.

Withdrawal symptoms

Withdrawal symptoms like anxiety, insomnia, sweating, nausea, tremors, and seizures manifesting upon reducing or discontinuing GHB use.


Increasing need for larger GHB doses to attain desired effects indicating the development of tolerance to GHB.

Physical symptoms

Dizziness, confusion, slurred speech, impaired coordination, nausea, and vomiting.

Mood changes

Irritability, aggression, depression, and anxiety.

Memory loss

Blackouts or memory gaps after GHB use.

Risky behaviors

Engaging in risky sexual behavior, driving under GHB influence, and other dangerous activities while using the drug.

GHB Addiction Symptoms

GHB addiction is classified as a substance use disorder. Its criteria are listed in DSM-5-TR (fifth revised edition of APA’s Diagnostic and Statistical Manual of Mental Disorders) as follows:

  1. Engaging in GHB use in quantities or durations surpassing the initially intended levels.
  2. Expressing a desire to reduce or discontinue use but encountering difficulty in doing so.
  3. Devoting lots of time to acquiring, using, and recuperating from the effects of GHB.
  4. Encountering intense cravings for GHB.
  5. Neglecting personal or professional responsibilities due to GHB use.
  6. Persisting in substance use despite its contribution to social or interpersonal issues.
  7. Forsaking social, recreational, or occupational activities and withdrawing from relationships to enable substance use.
  8. Using GHB in hazardous situations, such as while operating a vehicle.
  9. Continuing substance use despite awareness of physical or psychological issues caused or worsened by such use.
  10. Developing tolerance, necessitating increased substance amounts for desired effects.
  11. Experiencing unpleasant or uncomfortable GHB withdrawal symptoms upon discontinuation.

Treatment for GHB Addiction

Withdrawal symptoms of GHB may present when someone first stops using the drug, especially if their body has developed dependence on the substance for normal functioning. GHB withdrawal symptoms commonly include anxiety, insomnia, tremors, sweating, elevated heart rate, and psychotic thoughts. Medical supervision and addiction treatment within a detox facility or rehabilitation center is often the most effective springboard for ongoing treatment.

There are currently no established medications specifically for treating GHB addiction. In certain cases, controlled doses of benzodiazepines, antidepressants, or anticonvulsants may be prescribed as part of the treatment. Recovery professionals advocate confronting GHB addiction with a comprehensive treatment plan that emphasizes positive decision-making, overall health enhancements, and the acquisition of coping skills.

Following the detox phase, ongoing treatment takes place in an inpatient or outpatient setting to address the behavioral and emotional aspects of addiction. In inpatient rehab, individuals reside at the treatment center, receiving 24/7 care, support, and treatment, including individual and group counseling, behavioral therapies, and education. Outpatient services, by contrast allow individuals to live at home or in a sober living environment while attending the same treatments, programs, and therapies offered at residential rehab.

Regardless of the rehab setting, various behavioral therapies may be employed. CBT (cognitive behavioral therapy), proven effective for CNS depressant addiction, assists in identifying and modifying unhelpful or negative thoughts and behaviors impacting substance use. It imparts coping, stress management, and relapse prevention skills to streamline sustained recovery.

An image of the Gratitude Lodge facility, where addiction treatment is available

Get Treatment for GHB Addiction at Gratitude Lodge

If you or someone that you care about is addicted to GHB, we offer a variety of addiction treatment programs at Gratitude Lodge. We have inclusive and pet-friendly rehab centers in Long Beach and Newport Beach, CA, where you can begin your recovery the right way.

During supervised medical detoxification, you can take advantage of medications approved by the FDA to reduce the intensity of the withdrawal process. You will also benefit from around-the-clock care, reducing the chance of complications or relapse derailing your early recovery.

After about a week of detox, you can move into ongoing inpatient treatment at one of our beachside facilities. All Gratitude Lodge treatment programs mix holistic and science-based treatments, such as:

Call 800-994-2184 and get immediate assistance combating GHB addiction in California.

Want to learn more?

Recent Articles

Begin your journey
to recovery.

Get evidence-based treatment in a peaceful location, with a
team of dedicated, expert staff. 
Share on Facebook
Share on Twitter
Share on Linkedin
Share on Email
Joe Gilmore

Joseph Gilmore

Joseph Gilmore has been working in the addiction industry for half a decade and has been writing about addiction and substance abuse treatment during that time. He has experience working for facilities all across the country. Connect with Joe on LinkedIn.
Jenni Bussi

Jenni Busse MS, LPCC

Jenni Busse MS, LPSS is the Clinical Director at Gratitude Lodge. Jenni oversees the clinical program and the clinical team at Gratitude Lodge as a whole. Jenni has worked in treatment for almost 14 years. Her background as a licensed therapist and her passion for helping others intersected with addiction recovery when she started working primarily in detox residential treatment.

Drug detox can vary according to the patient’s addiction factors, including the substance abused, how long the addiction has lasted, the patient’s medical condition, if any other disorders are present, and more. Our skilled and credentialed team at Gratitude Lodge work closely with every patient going through drug detox, facilitating the beginnings of a successful recovery at our rehab addiction centers in Orange County, CA.

Drug detox can vary according to the patient’s addiction factors, including the substance abused, how long the addiction has lasted, the patient’s medical condition, if any other disorders are present, and more. Our skilled and credentialed team at Gratitude Lodge work closely with every patient going through drug detox.

Many patients don’t realize the toxicity of prolonged alcohol abuse and how it affects the body. Alcohol detox at the luxurious rehab addiction centers at Gratitude Lodge leeches your body of these toxins in preparation for successful treatment for drugs and alcohol abuse. Alcohol detox may not take as long or produce severe withdrawal symptoms, but it is still an essential beginning to your recovery.

Many patients don’t realize the toxicity of prolonged alcohol abuse and how it affects the body. Alcohol detox at the luxurious rehab addiction centers at Gratitude Lodge leeches your body of these toxins in preparation for successful treatment for drugs and alcohol abuse.
an image of clients representing drug detox california

Holistic Therapy

Our holistic therapy treatments offer a full-scope approach to recovery, addressing your mind, body, and emotions as part of a comprehensive treatment plan. This therapy is designed to help address underlying issues and integrate alternative therapies to promote overall health and well-being.
Gratitude Lodge clients laughing, representing drug detox california


An essential part of your treatment experience, we offer individual (CBT and DBT talk therapy) and group addiction treatment counseling to help you explore and address the emotional component of addiction, providing you with the tools, self-awareness, and empowerment you need to maintain recovery.
woman at beach representing drug detox in california

Dual Diagnosis

Dual Diagnosis is a highly effective addiction treatment that addresses substance use and mental health disorders simultaneously. Often co-occurring, these disorders are best managed when treated together with specific and targeted therapy.
an image of a client and therapist at Gratitude Lodge's Long Beach addiction treatment center

Medication-Assisted Treatment (MAT)

Medication-Assisted Treatment provides you with FDA-approved medications to help ease the symptoms of withdrawal while you’re in treatment. This makes the detox process easier and safer, as well as increasing the chances of a successful recovery.
an image of clients outside after getting help at Gratitude Lodge's rehab in Long Beach, California

Sober Living

Sober living provides a supportive and substance-free living environment for your ongoing recovery. We partner with a number of upscale and carefully vetted sober living homes that are available to our clients after inpatient alcohol and drug addiction treatment.
an image of clients at Gratitude Lodge's drug rehab program

Outpatient Treatment

Once detox and inpatient are complete, we provide an easy transition to outpatient care through our hand-selected partners. This program offers a more flexible approach, allowing you to ease back in to daily life while still receiving frequent & effective care.
An image of clients going through inpatient substance abuse treatment


Inpatient treatment provides an intensive and comprehensive addiction treatment program in a structured environment. You will receive 24/7 expert care, therapy, and support as you build your foundation for long-term recovery.
an image of clients at clients at Gratitude Lodge's representing fear in recovery

Drug & Alcohol Detox

A crucial first step in the recovery process, our detox program provides a comfortable, medically supervised environment that addresses the physical aspect of addiction and eliminates substances from your body.

Use Our 24 Hour text line. You can ask questions about our program, the admissions process, and more.