September 8, 2023

Barbiturate Overdose: Signs, Symptoms, & Treatment

image of a woman representing barbiturate overdose

Barbiturates are controlled substances that induce relaxation and drowsiness. Barbiturate overdose, also known as acute barbiturate poisoning, occurs when someone consumes more of the medication than prescribed, whether deliberately or accidentally. Barbiturates overdose can have life-threatening consequences. The abuse of barbiturate drugs increases the chance of overdose.

What is a Barbiturate Overdose?

What is barbiturate overdose, then? A barbiturate overdose occurs when an individual ingests an excessive amount of barbiturate medications, resulting in toxic levels of the drug accumulating in their body. Barbiturates act as depressants of the CNS (central nervous system) and were commonly prescribed in the past to treat conditions like insomnia, anxiety, and seizures. Due to their high potential for abuse and overdose, their medical use has significantly decreased in recent years.

Barbiturates work by depressing activity in the CNS, triggering effects like:

  • Sedation
  • Relaxation
  • Reduced anxiety

When taken as prescribed by a healthcare professional, barbiturates can provide therapeutic benefits. That said, misusing the medication by taking higher doses than recommended is associated with adverse outcomes that include overdose.

An overdose occurs when the body cannot effectively process the excessive amount of barbiturate, overwhelming its systems and leading to a range of symptoms. The severity of an overdose can vary based on factors such as:

  • Type of barbiturate
  • Dosag
  • Tolerance
  • Health status

Acute barbiturate intoxication is a serious and potentially life-threatening situation that requires immediate medical attention. It can result from accidentally taking too much of the medication or intentionally misusing the drug for recreational purposes. Due to the risks associated with barbiturate overdose, their medical use is now limited, and alternative medications with safer profiles are often preferred.

The symptoms of a barbiturate overdose can range from mild to severe and can affect various bodily functions, including the respiratory system, cardiovascular system, and central nervous system. Prompt medical intervention can prevent complications and ensure safety. If you suspect a barbiturate overdose in yourself or someone else, seek immediate medical help to prevent further harm and receive appropriate treatment.

image of woman representing the question what is a barbiturate overdose

Barbiturate Overdose Symptoms

The symptoms of a barbiturate overdose may vary in severity depending on the amount consumed and individual tolerance. Common symptoms include:

  • Drowsiness: Excessive sleepiness or difficulty staying awake.
  • Slurred speech: Impaired speech that sounds slow and unclear.
  • Confusion: Disorientation and difficulty thinking clearly.
  • Impaired coordination: Difficulty walking or performing tasks that require physical coordination.
  • Slow breathing: Shallow or slow breathing, which can lead to respiratory distress.
  • Hypotension: Low blood pressure, which may result in dizziness or fainting.
  • Slow heart rate: Bradycardia, or a slower-than-normal heart rate.
  • Unconsciousness: Loss of consciousness and inability to respond to stimuli.
  • Coma: A prolonged state of unconsciousness with little to no response.

Severe cases of barbiturate overdose can result in life-threatening respiratory failure, cardiac arrest, and death.

Getting Help for a Barbiturate Overdose

Getting help for a barbiturate overdose is a critical and time-sensitive matter that requires immediate action. If you suspect that someone is experiencing a barbiturate overdose, follow these steps to ensure their safety and well-being:

Call 911

The first and most important step is to call emergency services right away. If you are unsure whether an overdose has occurred but notice any alarming symptoms such as difficulty breathing, confusion, loss of consciousness, or severe drowsiness, don’t hesitate to call for professional help.

Stay with the person

While waiting for medical assistance to arrive, stay with the person who has overdosed. If the person loses consciousness, roll them onto their side to prevent choking in case of vomiting.

Provide information to the emergency responders

If you have any information about the substances the person may have taken, share it with the medical professionals when they arrive. Knowing the types and amounts of drugs involved can assist in providing appropriate treatment.

Avoid trying to sober up the person

Do not attempt to make the person vomit, give them food or drinks, or use home remedies. These actions can worsen the situation and delay proper medical treatment.

Administer naloxone (if applicable)

If you suspect the person has mixed barbiturates with opioids, and you have access to naloxone (a medication that reverses opioid overdoses), follow the instructions provided with the naloxone kit. However, remember that naloxone cannot reverse a barbiturate-induced coma.

Remain calm

While the situation may be distressing, try to remain as calm as possible. Medical professionals are trained to handle overdose situations and will do their best to provide the necessary care.

Support after treatment

Once the person receives medical treatment, their recovery may involve ongoing medical care and psychological support. Encourage them to seek professional help for substance misuse or addiction, as well as any underlying mental health issues that may contribute to their substance use.

Remember that time is of the essence when dealing with a barbiturate overdose. The prompt response of medical professionals can make a significant difference in the person’s chances of recovery. Prioritize their safety and well-being and encourage them to seek appropriate treatment and support for their overall health and recovery journey.

an image of Gratitude Lodge's acute barbiturate poisoning treatment center

Get Treatment for Barbiturate Addiction at Gratitude Lodge

If you have developed an addiction to barbiturates, we offer a full range of drug addiction and detox treatment programs at Gratitude Lodge in Southern California. We have pet-friendly treatment facilities located in Long Beach and Newport Beach, CA.

Choosing our medical detoxification program connects you with medical professionals who can offer emotional guidance as well as medications to streamline the barbiturate withdrawal process. Detox addresses the issue of physical dependence and paves the way for ongoing treatment. During a 30-day inpatient program, you can access the following treatments:

Barbiturate addiction is treatable with the right personalized blend of treatment. Call admissions at 800-994-2184 for immediate assistance.

Want to learn more?

Recent Articles

Begin your journey
to recovery.

Get evidence-based treatment in a peaceful location, with a
team of dedicated, expert staff. 
Share on Facebook
Share on Twitter
Share on Linkedin
Share on Email
Joe Gilmore

Joseph Gilmore

Joseph Gilmore has been working in the addiction industry for half a decade and has been writing about addiction and substance abuse treatment during that time. He has experience working for facilities all across the country. Connect with Joe on LinkedIn.
Jenni Bussi

Jenni Busse MS, LPCC

Jenni Busse MS, LPSS is the Clinical Director at Gratitude Lodge. Jenni oversees the clinical program and the clinical team at Gratitude Lodge as a whole. Jenni has worked in treatment for almost 14 years. Her background as a licensed therapist and her passion for helping others intersected with addiction recovery when she started working primarily in detox residential treatment.

Drug detox can vary according to the patient’s addiction factors, including the substance abused, how long the addiction has lasted, the patient’s medical condition, if any other disorders are present, and more. Our skilled and credentialed team at Gratitude Lodge work closely with every patient going through drug detox, facilitating the beginnings of a successful recovery at our rehab addiction centers in Orange County, CA.

Drug detox can vary according to the patient’s addiction factors, including the substance abused, how long the addiction has lasted, the patient’s medical condition, if any other disorders are present, and more. Our skilled and credentialed team at Gratitude Lodge work closely with every patient going through drug detox.

Many patients don’t realize the toxicity of prolonged alcohol abuse and how it affects the body. Alcohol detox at the luxurious rehab addiction centers at Gratitude Lodge leeches your body of these toxins in preparation for successful treatment for drugs and alcohol abuse. Alcohol detox may not take as long or produce severe withdrawal symptoms, but it is still an essential beginning to your recovery.

Many patients don’t realize the toxicity of prolonged alcohol abuse and how it affects the body. Alcohol detox at the luxurious rehab addiction centers at Gratitude Lodge leeches your body of these toxins in preparation for successful treatment for drugs and alcohol abuse.
an image of clients getting fresh air representing life skills in addiction recovery

Holistic Therapy

Our holistic therapy treatments offer a full-scope approach to recovery, addressing your mind, body, and emotions as part of a comprehensive treatment plan. This therapy is designed to help address underlying issues and integrate alternative therapies to promote overall health and well-being.
Gratitude Lodge clients laughing, representing fear in recovery


An essential part of your treatment experience, we offer individual (CBT and DBT talk therapy) and group addiction treatment counseling to help you explore and address the emotional component of addiction, providing you with the tools, self-awareness, and empowerment you need to maintain recovery.
woman at beach representing low dopamine

Dual Diagnosis

Dual Diagnosis is a highly effective addiction treatment that addresses substance use and mental health disorders simultaneously. Often co-occurring, these disorders are best managed when treated together with specific and targeted therapy.
an image of a client and therapist at Gratitude Lodge's Long Beach addiction treatment center

Medication-Assisted Treatment (MAT)

Medication-Assisted Treatment provides you with FDA-approved medications to help ease the symptoms of withdrawal while you’re in treatment. This makes the detox process easier and safer, as well as increasing the chances of a successful recovery.
an image of clients outside after getting help at Gratitude Lodge's rehab in Long Beach, California

Sober Living

Sober living provides a supportive and substance-free living environment for your ongoing recovery. We partner with a number of upscale and carefully vetted sober living homes that are available to our clients after inpatient alcohol and drug addiction treatment.
an image of clients at Gratitude Lodge's 12-step program orange county

Outpatient Treatment

Once detox and inpatient are complete, we provide an easy transition to outpatient care through our hand-selected partners. This program offers a more flexible approach, allowing you to ease back in to daily life while still receiving frequent & effective care.
An image of clients going through inpatient substance abuse treatment


Inpatient treatment provides an intensive and comprehensive addiction treatment program in a structured environment. You will receive 24/7 expert care, therapy, and support as you build your foundation for long-term recovery.
an image of clients at clients at Gratitude Lodge's representing fear in recovery

Drug & Alcohol Detox

A crucial first step in the recovery process, our detox program provides a comfortable, medically supervised environment that addresses the physical aspect of addiction and eliminates substances from your body.

Use Our 24 Hour text line. You can ask questions about our program, the admissions process, and more.