Kratom: Uses, Side Effects, & More

Updated February 10, 2026

An image of Karena Mathis, author for gratitude lodge
Authored By:

Karena Mathis

Edited By

Amy Leifeste

Medically Reviewed By

Sean O'Neill
MS, LMFT 112879

Explore treatment options today. For general drug info, contact your doctor.

Kratom: Uses, Side Effects, & More

Updated February 10, 2026

Authored By:

Karena Mathis

Edited By

Amy Leifeste

Explore treatment options today. For general drug info, contact your doctor.

Kratom, an extract from the Mitragyna tree, has garnered considerable attention for its potential therapeutic effects and the controversies surrounding its safety, as it is not FDA-approved.

Kratom is particularly popular because it offers both energizing and sedative effects, depending on the dosage, which gives it a wide range of uses. However, kratom may be dangerous, and some studies even show its lack of efficacy.

If youโ€™re wondering what kratom is and what it can do, youโ€™re in the right place. This blog will explore everything from its uses to the associated risks and side effects.

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What Is Kratom?

Kratom, known scientifically as Mitragyna speciosa, is a tropical tree native to Southeast Asia. Its leaves have been utilized for centuries for their psychoactive properties. Traditionally, it has been consumed in various forms, including kratom powder, kratom pills, kratom capsules, and even kratom drinks, for purposes like pain relief, mood enhancement, and energy boosts. It can produce opioid-like and stimulant-like feelings, making it a popular supplement for those looking for energy. However, kratom is not as effective or safe as it initially comes off.

Mitragyna Speciosa Leaf

The leaves of the mitragyna speciosa tree contain active compounds, mainly mitragynine and 7-hydroxy mitragynine. These compounds interact with opioid receptors in the brain, leading to varied effects of kratom that can be both stimulating and sedative, depending on the dose and strain used.

Ways to Take Kratom

Kratom can be consumed in several ways, including:

  • Kratom Powder: Dried leaves ground into a fine powder, often mixed into drinks or smoothies.
  • Kratom Capsules: Pre-measured doses popular for on-the-go use.
  • Kratom Gummies: Available in various flavors and milligram counts.
  • Kratom Extract: Concentrated forms that can offer potent effects.
  • Kratom Shots: Liquid formulations designed for quick consumption.
  • Kratom Drink: Infusions made by steeping kratom leaves in hot water.

What Does Kratom Do?

The effects of kratom can vary significantly based on the strain and dosage. For instance, Bali red kratom is known for its balanced effects, offering sedative and pain-relieving properties. Lower doses often lead to increased energy and focus, while higher doses may induce sedation and pain relief, making kratom a popular choice for those seeking kratom for pain management. Kratom has been used for many different reasons, including the following:

  • To manage drug withdrawal symptoms
  • To get high
  • To feel sedative effects and assist with relaxation and sleep
  • For pain management
  • To manage mental health problems

While some users advocate for its benefits, research is inclusive of the efficacy of kratom for these purposes. Itโ€™s essential to understand the potential kratom side effects to understand the risks involved when taking kratom.

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Kratom Side Effects

Understanding the side effects of kratom is crucial, as its impact on the body can vary from person to person. While some users report positive effects, kratom can also cause unwanted short-term symptoms that range from mild discomfort to more serious health concerns.

Short-Term Effects

Short-term side effects of kratom can include:

  • Nausea
  • Dry mouth
  • Constipation
  • Increased heart rate
  • Anxiety or agitation
  • Alertness
  • Physical energy
  • Talkativeness
  • Dizziness
  • Insomnia
  • Hallucinations
  • Sedation (in high doses)

Long-Term Effects

Long-term use of kratom may result in more severe health issues, such as:

  • Liver damage: Some studies suggest that chronic kratom use may be linked to liver toxicity, leading to serious complications like liver disease.
  • Hormonal changes: Extended use of kratom can affect hormone levels, potentially leading to issues such as reduced libido, infertility, or hormonal imbalances.
  • Weight loss: Kratom can cause nausea and loss of appetite which may lead to weight loss.
  • Psychosis: Kratom can lead to psychosis in some individuals due to its pharmacological properties, dosage, and personal susceptibility.
  • Addiction: Because of its reported opioid-like effects, kratom may cause addiction in some individuals, possibly leading to overdose or death.
  • Gastrointestinal issues: Long-term users often report chronic constipation and other gastrointestinal issues, which can lead to further complications.

In some instances, kratom may even cause death. Because kratom has been minimally researched, the long-term health effects are still not widely understood, and there may be long-term effects not listed above.

Kratom Side Effects: Heart

One concerning aspect is that some users have reported kratom side effects involving heart issues, such as elevated heart rate and blood pressure. This makes it crucial for individuals with cardiovascular conditions to exercise caution.

Kratom Warnings & Dangers

Kratom remains poorly researched, making it a high-risk substance. It is especially dangerous when mixed with other substances because of its potential to have its effects amplified.

Is Kratom Bad for You?

While some people find benefits in kratom, there are significant risks involved. The potential for addiction and withdrawal symptoms has been documented, raising the question: is kratom bad for you? The FDA has not approved kratom, and its safety profile is still under investigation; however, it is not recommended to eat or take kratom.

Kratom Interactions

Kratom can interact with various medications, including antidepressants and opioids, leading to potentially dangerous side effects. Itโ€™s essential to consult a healthcare professional before mixing substances. The following are things to be cautious about if you are considering taking kratom.

  • Opioids and CNS Depressants: Mixing kratom with other opioids or central nervous system depressants can amplify sedative effects, increasing the risk of respiratory depression, overdose, and even death.
  • Stimulants: Combining kratom with stimulants can lead to unpredictable effects on the heart and nervous system, potentially causing severe anxiety, panic attacks, or cardiovascular strain.
  • Antidepressants: Some reports suggest that kratom may interact with antidepressants, potentially leading to serotonin syndrome, a dangerous condition resulting from excessive serotonin levels.

Kratom Addiction Risk

There is a real risk of developing a dependence on kratom. Regular use can lead to tolerance, requiring higher doses for the same effects. Kratom withdrawal symptoms may include irritability, insomnia, and muscle aches.

Can You Die From Kratom Overdose?

While fatalities from kratom are rare, they can occur, particularly when combined with other substances. Overdose symptoms may include severe respiratory depression, necessitating immediate medical attention.

Lack of Regulation and Research

The kratom market is largely unregulated, which raises concerns about product quality and safety. Many products may not contain what they claim, and contamination with other substances is possible. Moreover, more research is needed to fully understand the long-term effects of kratom use.

Get Insurance-Covered Addiction Treatment at Gratitude Lodge

If you or someone you care about is facing challenges with kratom addiction or dependence, Gratitude Lodge is ready to assist. Our renowned addiction treatment center offers upscale accommodations, a compassionate and dedicated staff, and a beautiful setting.

At Gratitude Lodge, we provide comprehensive support for substance abuse through various treatment methods, including:

  • Personalized treatment plans
  • Medication-assisted treatment
  • Cognitive Behavioral Therapy (CBT)
  • Dialectical Behavioral Therapy (DBT)
  • Regular group beach outings and adventure therapy activities
  • Aftercare support and a vibrant alumni network

Embark on your journey to lasting recovery and reclaim your life. Reach out to us today to learn more about joining Gratitude Lodge or to discuss payment options. We accept insurance and offer a free insurance verification for those interested.

Take the first step by calling us at 844-576-0144.

Sources

  1. https://nida.nih.gov/research-topics/kratom#affect-body
  2. https://www.dea.gov/sites/default/files/2020-06/Kratom-2020_0.pdf

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