Methaqualone Withdrawal: Symptoms, Timeline & Treatment

An image of Karena Mathis, author for gratitude lodge
Authored By:

Karena Mathis

Edited By

Amy Leifeste

Medically Reviewed By

Sean O'Neill
MS, LMFT 112879

Explore treatment options today. For general drug info, contact your doctor.

Methaqualone Withdrawal: Symptoms, Timeline & Treatment

Authored By:

Karena Mathis

Edited By

Amy Leifeste

Explore treatment options today. For general drug info, contact your doctor.

Methaqualone is a sedative-hypnotic medication that was used to treat insomnia and anxiety. However, it gained popularity as a recreational substance with a significantly high risk of addiction. Currently, in many countries, methaqualone is no longer recognized for medical purposes and is prohibited to own, produce, or sell.

When someone is misusing or dependent on methaqualone, a detox facility or withdrawal treatment center for methaqualone can offer professional assistance to individuals requiring support. Ideally, detoxing from methaqualone must take place under the supervision of qualified professionals because methaqualone withdrawal symptoms can be hazardous.

Gratitude Lodge offers a safe and comfortable environment for a methaqualone detox under medical supervision. If you or a loved one are struggling with methaqualone addiction and want to quit, hereโ€™s everything you need to know about methaqualone withdrawal and detoxing from methaqualone.

Where Youโ€™d Be Staying

We strive to provide a comfortable, home-like environment during your recovery journey. Browse our facility images below to take a look at our upscale residential facilities.

What is Methaqualone?

Methaqualone is a highly powerful synthetic sedative-hypnotic medication that functions as a central nervous system depressant. It was frequently utilized to help manage insomnia, serve as a sedative, or act as a muscle relaxant. Methaqualone has effects similar to barbiturates and is extremely addictive.

These medications, marked with the number “714” on the pill, were first presented as a secure barbiturate alternative for promoting sleep, but were subsequently demonstrated to cause addiction and withdrawal effects akin to other prescribed barbiturates

Methaqualone was first produced in the United States and marketed as Quaalude, Sopor, Parest, and Mecquin. However, production was stopped in 1984 because of severe abuse issues and negative effects on users.

Currently, methaqualone is categorized as a Schedule I substance by the United States Drug Enforcement Agency, making it unlawful to produce, own, sell, or distribute.

What Is Methaqualone Withdrawal Like?

Methaqualone withdrawal symptoms have extremely uncomfortable physical and psychological effects, their occurrence can lead an individual to keep using the drug to escape them. This can cause addiction.

Within a few days of methaqualone use, users may build tolerance and become dependent. Moreover, tolerance puts an individual at risk of overdose since a larger quantity of the substance is required to achieve the desired effect.

When someone is tolerant of or dependent on a drug, stopping suddenly can lead to withdrawal symptoms. This happens because the abrupt discontinuation of methaqualone causes the brain and body to overcompensate for the lack of the drug.

Withdrawal Symptoms of Methaqualone

Withdrawal from methaqualone can cause the following symptoms:

  1. Hallucinations
  2. Irregular heartbeat or increased heart rate
  3. Sweating
  4. Confusion
  5. Anxiety
  6. Fatigue
  7. Insomnia
  8. Restlessness
  9. Tremors
  10. Tingling sensations in the hands and feet
  11. Seizures
  12. Dizziness
  13. Nausea and vomiting
  14. Digestive disturbances
  15. Headaches

The withdrawal symptoms methaqualone causes vary in severity based on the userโ€™s tolerance, how often it is consumed, whether it was consumed in combination with other drugs, and the patientโ€™s current mental and physical health.

Methaqualone Withdrawal Timeline

Methaqualone withdrawal symptoms typically start around 12 to 24 hours after the final intake of methaqualone, reaching their peak 24 to 48 hours afterward.

While most symptoms usually subside within a week or so, certain psychological symptoms can persist for weeks or even months after methaqualone withdrawals.

Hereโ€™s a general timeline for barbiturate withdrawal:

  • Two to Three Days: The withdrawal symptoms worsen. Among these are nausea and vomiting, increased heart rate, anxiety, seizures, and hallucinations.
  • Three Days to a Week: Symptoms of withdrawal will begin to fade.
  • More Than Two Weeks: By this point, most of the barbiturate withdrawal symptoms should have disappeared.

Why Methaqualone Abuse Causes Withdrawal

Methaqualone is a quinazolinone derivative, a compound that exhibits biological activities significant for medicine. The medication exerts its effects by regulating the activity of receptors for the inhibitory neurotransmitter gamma-aminobutyric acid (GABA), which decreases the transmission of neural signals in the brain. Thus, methaqualone causes sedation, with the intensity varying based on the dosage.

When an individual tries getting off methaqualone abruptly, the brain cannot adjust to the sudden lack of the drug since it is used to its sedative and calming effects. This manifests as various physical and psychological withdrawal symptoms, including headaches, sleep disturbances, anxiety, and body aches.

We Accept Most Major Insurance

View our wide selection of accepted providers.
Donโ€™t see yours? Call our admissions team for help.

View our wide selection of accepted providers. Donโ€™t see yours? Call our admissions team for help.

Struggling with addiction? We can help.

Our insurance-covered rehab offers premier treatment for drug addiction, alcohol addiction, & mental health disorders. Call our friendly team today to get started.

What Is Detox for Methaqualone Like?

A methaqualone detoxification program typically serves as the initial stage in the treatment journey, providing an average detox duration of seven to 10 days. As stated previously, withdrawal symptoms typically start around 12 to 24 hours following the last use of methaqualone, reaching their peak 24 to 48 hours, and gradually subsiding over subsequent weeks.

Facilities offering detox from methaqualone are typically residential programs that enable close supervision of substance users throughout the early withdrawal period. Stopping methaqualone suddenly can lead to life-threatening symptoms with serious long-term health risks, so detoxification is best conducted with medical oversight.

Medically overseen methaqualone withdrawal treatment can lessen the severity of withdrawal symptoms and also help resolve some completely. Medically supervised detox for methaqualone also enhances the likelihood of achieving a safe and effective recovery from methaqualone addiction. It is essential for the patientโ€™s physical and mental health, as well as for a successful recovery, that methaqualone detox occurs under the constant oversight of trained medical staff.

Methaqualone withdrawal treatment centers focus on physical detoxification from the substance and also offer more extensive assistance, including counseling and behavioral therapies. In addition to the detox process, drugs might be given to reduce pain and lower anxiety from withdrawal symptoms.

What Happens After Methaqualone Detox?

Additional treatment following detox is essential to address the underlying psychosocial problems linked to the addiction. Therapies like psychotherapy, counseling, and family therapy assist individuals in attaining a well-rounded recovery.

FAQs

How long do methaqualone withdrawals last?

2-3 days: Symptoms usually begin a few hours after discontinuation of the drug and worsen within a few days. Symptoms of withdrawal generally begin to decrease in intensity after a week and usually subside within two weeks.

How long does it take to detox from methaqualone?

The duration required for full detoxification differs based on the length of use and the individual patient. However, symptoms of methaqualone withdrawal usually start around 12 to 24 hours after the final dose, peaking within 24 to 72 hours post last dose, and subsiding gradually in the coming weeks.

What are the stages of a drug detox?

As the body processes the drug, you will experience three phases of detoxification: emerging withdrawal symptoms, peak/maximum withdrawal symptoms, and subsiding/diminishing withdrawal symptoms. The particular symptoms you encounter will differ based on the specific substance in question and the seriousness of the substance use disorder.

What happens when the body goes through detox?

During detox, the effects of the drug start diminishing, and the body experiences mild and then intense withdrawal symptoms. These include shaking, perspiration, sleeplessness, fast heartbeat, and elevated blood pressure, alongside a higher likelihood of seizures and other health crises.

What are the side effects of stopping methaqualone?

The sudden cessation of methaqualone could lead to withdrawal symptoms such as anxiety, agitation, insomnia, tremors, headaches, muscle aches, nausea, and vomiting.

What drug has the worst withdrawal symptoms?

Heroin, cocaine, and crystal meth are reported to have the worst withdrawal symptoms since they significantly affect dopamine levels and most often lead to addiction.

What are the stages of drug withdrawal?

  1. Deciding to quit
  2. Manifestation of withdrawal symptoms
  3. Withdrawal symptoms increase in intensity
  4. Symptoms peak and then decrease in intensity
  5. Recurrence or persistence of certain withdrawal symptoms

How long does it take to completely detox?

Generally, a person can eliminate substances from their system in about a week (although cravings might linger for several months following that). Some of the most severe symptoms of withdrawal are generally not life-threatening, such as including vomiting and diarrhea. Nonetheless, dehydration resulting from these symptoms can be dangerous.

Overcome Methaqualone Addiction with Gratitude Lodge

If you or a dear one needs assistance with methaqualone addiction, Gratitude Lodge in Southern California is here to help you.

We offer a monitored medical detox, which is the easiest route to continued care for sedative use disorder. We can assist you in reaching this goal at our accredited medical detox facilities situated in San Diego, Newport Beach, and Long Beach. With emotional and clinical support accessible 24/7, you can overcome reliance on the drug, moving straight into a continuous treatment plan after detox.

You can select from these available treatment options for sedative dependency:

  • 30-day residential rehabilitation
  • IOP (intensive outpatient treatment)
  • Program for treating dual diagnosis

Every addiction treatment program at Gratitude Lodge offers individualized care that incorporates a variety of evidence-based therapies and holistic approaches. These include:

  • Talk therapy
  • Group counseling
  • Motivational therapy
  • Family counseling
  • Holistic therapies

Upon leaving Gratitude Lodge, you will have a comprehensive aftercare plan to enhance your likelihood of long-term sobriety. This will encompass strategies for preventing relapse, managing relapse, coping methods, and continuous outpatient care if necessary.

When you feel prepared to transition from methaqualone misuse and dependence into lasting recovery, rest assured that we at Gratitude Lodge are here to help.

Contact 844-576-0144 now for immediate assistance.

Sources

  1. https://www.dea.gov/taxonomy/term/316

ndent on methaqualone, a detox facility or withdrawal treatment center for methaqualone can offer professional assistance to individuals requiring support. Ideally, detoxing from methaqualone must take place under the supervision of qualified professionals because methaqualone withdrawal symptoms can be hazardous.

Gratitude Lodge offers a safe and comfortable environment for a methaqualone detox under medical supervision. If you or a loved one are struggling with methaqualone addiction and want to quit, hereโ€™s everything you need to know about methaqualone withdrawal and detoxing from methaqualone.

Where Youโ€™d Be Staying

We strive to provide a comfortable, home-like environment during your recovery journey. Browse our facility images below to take a look at our upscale residential facilities.

What is Methaqualone?

Methaqualone is a highly powerful synthetic sedative-hypnotic medication that functions as a central nervous system depressant [2]. It was frequently utilized to help manage insomnia, serve as a sedative, or act as a muscle relaxant. Methaqualone has effects similar to barbiturates and is extremely addictive.

These medications, marked with the number “714” on the pill, were first presented as a secure barbiturate alternative for promoting sleep, but were subsequently demonstrated to cause addiction and withdrawal effects akin to other prescribed barbiturates

Methaqualone was first produced in the United States and marketed as Quaalude, Sopor, Parest, and Mecquin. However, production was stopped in 1984 because of severe abuse issues and negative effects on users.

Currently, methaqualone is categorized as a Schedule I substance by the United States Drug Enforcement Agency, making it unlawful to produce, own, sell, or distribute [3].

What Is Methaqualone Withdrawal Like?

Methaqualone withdrawal symptoms have extremely uncomfortable physical and psychological effects, their occurrence can lead an individual to keep using the drug to escape them. This can cause addiction.

Within a few days of methaqualone use, users may build tolerance and become dependent. Moreover, tolerance puts an individual at risk of overdose since a larger quantity of the substance is required to achieve the desired effect.

When someone is tolerant of or dependent on a drug, stopping suddenly can lead to withdrawal symptoms. This happens because the abrupt discontinuation of methaqualone causes the brain and body to overcompensate for the lack of the drug.

Withdrawal Symptoms of Methaqualone

Withdrawal from methaqualone can cause the following symptoms:

  • Hallucinations
  • Irregular heartbeat or increased heart rate
  • Sweating
  • Confusion
  • Anxiety
  • Fatigue
  • Insomnia
  • Restlessness
  • Tremors
  • Tingling sensations in the hands and feet
  • Seizures
  • Dizziness
  • Nausea and vomiting
  • Digestive disturbances
  • Headaches

The withdrawal symptoms methaqualone causes vary in severity based on the userโ€™s tolerance, how often it is consumed, whether it was consumed in combination with other drugs, and the patientโ€™s current mental and physical health.

Methaqualone Withdrawal Timeline

Methaqualone withdrawal symptoms typically start around 12 to 24 hours after the final intake of methaqualone, reaching their peak 24 to 48 hours afterward.

While most symptoms usually subside within a week or so, certain psychological symptoms can persist for weeks or even months after methaqualone withdrawals.

Hereโ€™s a general timeline for barbiturate withdrawal:

  • Two to Three Days: The withdrawal symptoms worsen. Among these are nausea and vomiting, increased heart rate, anxiety, seizures, and hallucinations.
  • Three Days to a Week: Symptoms of withdrawal will begin to fade.
  • More Than Two Weeks: By this point, most of the barbiturate withdrawal symptoms should have disappeared.

Why Methaqualone Abuse Causes Withdrawal

Methaqualone is a quinazolinone derivative, a compound that exhibits biological activities significant for medicine. The medication exerts its effects by regulating the activity of receptors for the inhibitory neurotransmitter gamma-aminobutyric acid (GABA), which decreases the transmission of neural signals in the brain. Thus, methaqualone causes sedation, with the intensity varying based on the dosage.

When an individual tries getting off methaqualone abruptly, the brain cannot adjust to the sudden lack of the drug since it is used to its sedative and calming effects. This manifests as various physical and psychological withdrawal symptoms, including headaches, sleep disturbances, anxiety, and body aches.

We Accept Most Major Insurance

View our wide selection of accepted providers.
Donโ€™t see yours? Call our admissions team for help.

View our wide selection of accepted providers. Donโ€™t see yours? Call our admissions team for help.

Struggling with addiction? We can help.

Our insurance-covered rehab offers premier treatment for drug addiction, alcohol addiction, & mental health disorders. Call our friendly team today to get started.

What Is Detox for Methaqualone Like?

A methaqualone detoxification program typically serves as the initial stage in the treatment journey, providing an average detox duration of seven to 10 days. As stated previously, withdrawal symptoms typically start around 12 to 24 hours following the last use of methaqualone, reaching their peak 24 to 48 hours, and gradually subsiding over subsequent weeks.

Facilities offering detox from methaqualone are typically residential programs that enable close supervision of substance users throughout the early withdrawal period. Stopping methaqualone suddenly can lead to life-threatening symptoms with serious long-term health risks, so detoxification is best conducted with medical oversight.

Medically overseen methaqualone withdrawal treatment can lessen the severity of withdrawal symptoms and also help resolve some completely. Medically supervised detox for methaqualone also enhances the likelihood of achieving a safe and effective recovery from methaqualone addiction. It is essential for the patientโ€™s physical and mental health, as well as for a successful recovery, that methaqualone detox occurs under the constant oversight of trained medical staff.

Methaqualone withdrawal treatment centers focus on physical detoxification from the substance and also offer more extensive assistance, including counseling and behavioral therapies. In addition to the detox process, drugs might be given to reduce pain and lower anxiety from withdrawal symptoms.

What Happens After Methaqualone Detox?

Additional treatment following detox is essential to address the underlying psychosocial problems linked to the addiction. Therapies like psychotherapy, counseling, and family therapy assist individuals in attaining a well-rounded recovery.

FAQs

How long do methaqualone withdrawals last?

2-3 days: Symptoms usually begin a few hours after discontinuation of the drug and worsen within a few days. Symptoms of withdrawal generally begin to decrease in intensity after a week and usually subside within two weeks.

How long does it take to detox from methaqualone?

The duration required for full detoxification differs based on the length of use and the individual patient. However, symptoms of methaqualone withdrawal usually start around 12 to 24 hours after the final dose, peaking within 24 to 72 hours post last dose, and subsiding gradually in the coming weeks.

What are the stages of a drug detox?

As the body processes the drug, you will experience three phases of detoxification: emerging withdrawal symptoms, peak/maximum withdrawal symptoms, and subsiding/diminishing withdrawal symptoms. The particular symptoms you encounter will differ based on the specific substance in question and the seriousness of the substance use disorder.

What happens when the body goes through detox?

During detox, the effects of the drug start diminishing, and the body experiences mild and then intense withdrawal symptoms. These include shaking, perspiration, sleeplessness, fast heartbeat, and elevated blood pressure, alongside a higher likelihood of seizures and other health crises.

What are the side effects of stopping methaqualone?

The sudden cessation of methaqualone could lead to withdrawal symptoms such as anxiety, agitation, insomnia, tremors, headaches, muscle aches, nausea, and vomiting.

What drug has the worst withdrawal symptoms?

Heroin, cocaine, and crystal meth are reported to have the worst withdrawal symptoms since they significantly affect dopamine levels and most often lead to addiction.

What are the stages of drug withdrawal?

There are 5 stages of drug withdrawal:

  1. Deciding to quit
  2. Manifestation of withdrawal symptoms
  3. Withdrawal symptoms increase in intensity
  4. Symptoms peak and then decrease in intensity
  5. Recurrence or persistence of certain withdrawal symptoms

How long does it take to completely detox?

Generally, a person can eliminate substances from their system in about a week (although cravings might linger for several months following that). Some of the most severe symptoms of withdrawal are generally not life-threatening, such as including vomiting and diarrhea. Nonetheless, dehydration resulting from these symptoms can be dangerous.

Overcome Methaqualone Addiction with Gratitude Lodge

If you or a dear one needs assistance with methaqualone addiction, Gratitude Lodge in Southern California is here to help you.

We offer a monitored medical detox, which is the easiest route to continued care for sedative use disorder. We can assist you in reaching this goal at our accredited medical detox facilities situated in San Diego, Newport Beach, and Long Beach. With emotional and clinical support accessible 24/7, you can overcome reliance on the drug, moving straight into a continuous treatment plan after detox.

You can select from these available treatment options for sedative dependency:

  • 30-day residential rehabilitation
  • IOP (intensive outpatient treatment)
  • Program for treating dual diagnosis

Every addiction treatment program at Gratitude Lodge offers individualized care that incorporates a variety of evidence-based therapies and holistic approaches. These include:

  • Talk therapy
  • Group counseling
  • Motivational therapy
  • Family counseling
  • Holistic therapies

Upon leaving Gratitude Lodge, you will have a comprehensive aftercare plan to enhance your likelihood of long-term sobriety. This will encompass strategies for preventing relapse, managing relapse, coping methods, and continuous outpatient care if necessary.

When you feel prepared to transition from methaqualone misuse and dependence into lasting recovery, rest assured that we at Gratitude Lodge are here to help.

Contact 844-576-0144 now for immediate assistance.

Sources

  1. https://www.dea.gov/taxonomy/term/316

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Jayla Bassi
6 October 2026
Google star 1Google star 2Google star 3Google star 4Google star 5
My time at gratitude lodge has been such an amazing experience, from the staff, to the food, to all the skills Iโ€™ve learned about myself along the way. The group facilitators are one of a kind, supportive, compassionate, and they have all changed my outlook of what I want for my future. As for the staff, Vinney has been a fantastic support through this, he always made me feel at home, like I wasnโ€™t just another person passing through this house. Nixon and Maya are the best faces to see when I wake up, they are always on top of it, making sure everything is in order, and always brought warmth into my life, and a great start to the day. Tiffany is a fantastic case manager, sheโ€™s very thorough with everything you need to set up for yourself, can always give great advice on any situation you might be having, and one of the sweetest people Iโ€™ve ever met. All of my therapy sessions were so helpful, Amir always made me feel so comfortable and relaxed, I would talk to him about anything and everything. So smart and would always breaks down my problems so I really understood my mental health, and what was the cause of it. Overall, I really have hope for my future, this place and these people has impacted my life in a way I never thought was possible. I recommend Gratitude Lodge to anyone who needs treatment and a very good support system to come with it.
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august genovese
6 October 2026
Google star 1Google star 2Google star 3Google star 4Google star 5
This was not my first time in treatment, but with the help and care of the staff here, hopefully my last. It was extremely structured, educational, and therapeutic. Vinney, Ally, Maya, Nixon, Amir, and Tiffany are people i consider staples in my recovery journey. As well as the rest of the staff there. I was guided, motivated, encouraged, listened to, and helped whenever i needed. This is a great facility that i hold near and dear to my heart and hope other people struggling with mental health or substance abuse get the privilege of attending!
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Rhonda Smith
1 October 2026
Google star 1Google star 2Google star 3Google star 4Google star 5
Hello I'm Rhonda Alcoholic I Can Actually Say Gratitude Lodge did it's work on person like myself. This place I will give Millions thumbs up. I felt at work was welcome with opening arms. The Case Manager Roger and The Therapist Joe Is truly appreciate and amazing. Brung me back to reality helped me understand that I wasn't alone through this addiction I am battling. If You or Anyone looking for a detox and rehab this is the most beautiful place to get back we're you need to be.. All the team Staff's is so so amazing not just one all of them show so much support and love to everyone.. Give Gratitude Lodge a ๐Ÿ’ฏ
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James K.
26 September 2026
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Gratitude Lodge is a great organization for anyone looking for a safe, supportive place to begin their recovery journey. If you're looking for a safe detox followed by a 30-day residential treatment stay, Gratitude Lodge provides an environment where you can step away from the chaos, find yourself, and surround yourself with supportive and encouraging people who genuinely want to see you succeed. The facility provides a safe, clean environment with wraparound case management, therapy, peer support, and a strong focus on helping each person become mentally, physically, and emotionally stable. Recovery isn't easy, but having the right environment and the right people around you can make a huge difference. If you or someone you love is struggling, reach out to Gratitude Lodge and take that first step. Five-star. Top-of-the-line treatment. A place where recovery is taken seriously. Respectfully, James T Krier
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Taylor profile picture
Taylor
24 September 2026
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Best program i have been in as far as treatment is concerned.
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Angela Carpenter
16 September 2026
Google star 1Google star 2Google star 3Google star 4Google star 5
Great facility. Staff was very supportive of my friend who went there. Tiffany was the staff member who updated us. You can tell she really cares and very knowledgeable. I would definetly recommend to anyone needing change.
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Richard A.
20 August 2026
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I had the pleasure of touring this detox and residential treatment facility, and I was truly impressed. From the moment I arrived, I was warmly greeted by the staff and clinical team. It was clear that they genuinely care about the people they serve and take the time to engage with each individual, making you feel like more than just a number. They also have a chef on-site who was cooking while I was there, and the delicious smell throughout the house made the environment feel even more welcoming and comforting. The location is amazing--just minutes away from Long Beach, with beautiful views of the water that create a peaceful, relaxing, and therapeutic atmosphere. Overall, I was amazed by this facility and would highly recommend it to anyone struggling with substance abuse and/or mental health challenges. The staff, environment, and level of care truly stood out to me.
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Ashley B.
1 June 2026
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Great place to do treatment in. Amazing staff, great groups. I had an amazing experience.
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Ashley B.
1 June 2026
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Great place to do treatment in. Amazing staff, great groups. I had an amazing experience.
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Amy T.
26 April 2026
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I called and Pramod was the name of the attendant on the addiction hotline and he was the best help . So kind and helpful when forwarding me to what i needed to do next With a list of places that could help ..
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Dargan Rogers
11 August 2025
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Gratitude Lodge is an amazing treatment program and the staff are great. I would highly recommend.
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