What Is Stilpane Syrup? Uses, Side Effects, & More

an image of cough syrup representing what is stilpane syrup?

Updated September 18, 2024

Authored By:

Joe Gilmore

Edited By

Amy Leifeste

Medically Reviewed By

Javier Rodriguez-Winter

Authored By:

Joe Gilmore

Edited By

Amy Leifeste

Medically Reviewed By

Javier Rodriguez-Winter

an image of cough syrup representing what is stilpane syrup?

Stilpane syrup is a combination medication used to relieve mild to moderate pain and reduce fever, containing paracetamol, codeine phosphate, and caffeine. While it can be helpful when used correctly, taking too much or using it the wrong way can cause serious health problems.

Read on to learn more about the dangers of abusing Stilpane syrup and discover how to get compassionate and effective opioid addiction treatment.

What Is Stilpane?

Stilpane syrup is a cough medicine that has codeine, paracetamol, and promethazine in it. It’s used to help with coughs from colds and upper respiratory infections. Promethazine is an antihistamine that helps with sneezing, runny nose, and watery eyes. Codeine reduces coughing by making it less intense. Paracetamol is an OTC painkiller also known as acetaminophen.

When used correctly with a doctor’s guidance, Stilpane syrup can be highly beneficial, but any misuse can be dangerous. Codeine is an opioid and taking too much can make people feel happy and relaxed, which can lead to abuse by those seeking a recreational high. Opioids also lead to the development of tolerance and dependence, which often leads to addiction.

Stilpane Syrup Ingredients

Stilpane syrup contains three main ingredients that help treat cough and cold symptoms. Here’s what each ingredient does and why it is important:

Codeine

Codeine is an opioid that helps reduce coughing. Opioids like codeine affect the brain and CNS (central nervous system) to ease the intensity of coughing.

  • How it works: Codeine changes how your brain senses pain and how you react to coughing.
  • Why it’s used: It helps stop persistent coughing, making it easier for people to sleep and recover from an illness.
  • Warning: Codeine can be addictive if not used correctly, so use it only as directed by a doctor.

Paracetamol

Paracetamol, also marketed as acetaminophen, is a common pain reliever and fever reducer.

  • How it works: Paracetamol reduces fever by affecting the heat-regulating part of the brain. It relieves pain by blocking the production of certain chemicals in the body that cause pain.
  • Why it’s used: It helps lower a fever and relieves headaches, sore throats, and other aches and pains that come with colds or infections.
  • Warning: Taking too much paracetamol can damage your liver, so follow the dosage instructions carefully.

Promethazine

Promethazine is an antihistamine that helps with symptoms like sneezing, a runny nose, and watery eyes.

  • How it works: Promethazine blocks the action of histamine, a substance in the body that causes allergic symptoms. It also has a calming effect that can help you sleep.
  • Why it’s used: It helps reduce symptoms like sneezing, runny nose, and itchy, watery eyes, making it easier to rest and recover from a cold.
  • Warning: Promethazine can make you feel drowsy, so it’s best to take it when you don’t need to be alert or operate machinery.

These ingredients make Stilpane syrup effective in treating coughs and other symptoms of colds and upper respiratory infections. Use the medication as directed by your healthcare provider to avoid serious side effects.

What Is Codeine?

Codeine is a medication that doctors often prescribe for mild to moderate pain, coughs, and sometimes for stomach problems like diarrhea. Other similar drugs include Vicodin, OxyContin, and Demerol.

Codeine is a controlled substance classified as a Schedule II drug by the DEA. This means it can be very addictive and should be used carefully. While it can help with symptoms, it doesn’t cure the underlying problem. People who use codeine as prescribed take only the amount their doctor tells them to.

What Does Codeine Do?

Opioids like codeine work by attaching to receptors in your brain and body. These opioid receptors are also where your body’s natural painkillers work, but opioids are much stronger. When codeine binds to these receptors, it blocks pain signals, so you don’t feel as much pain.

Opioid drugs, including codeine in cough syrups like Stilpane, trigger the brain’s reward center by releasing a chemical called dopamine. This makes you feel good and happy. However, this can also lead to addiction. Your brain starts to want that feeling again and again, which can lead to misuse of the drug.

When someone uses codeine repeatedly, their brain and body depend on it to feel pleasure. This is how addiction begins. 

Misusing cough syrup like Stilpane can cause serious health problems and affect personal relationships. Use codeine only as directed by a doctor to avoid these risks. If you or someone you know is struggling with addiction, seek help right away. Addiction is a chronic condition that usually gets worse when untreated.

Paracetamol & Codeine

Paracetamol and codeine work together in Stilpane syrup to relieve pain and reduce coughing. Paracetamol, also known as acetaminophen, helps lower fever and ease pain like headaches and sore throats. Codeine is an opioid that helps calm the cough reflex and provides additional pain relief. When combined, these ingredients can make you feel better when you have a cold or cough, but they must be used carefully to avoid side effects and addiction.

Common Uses of Stilpane Cough Syrup

Stilpane cough syrup is a medicine that doctors prescribe for different health problems. Here are some common uses of Stilpane cough syrup:

  1. Treating coughs: Stilpane cough syrup is often used to help reduce coughing. The codeine in the syrup helps to calm the cough reflex, making it easier to rest and sleep.
  2. Relieving pain: Stilpane contains paracetamol (acetaminophen), which helps to reduce pain. This can be useful for mild to moderate pain, such as headaches, sore throats, or muscle aches that often come with colds and flu.
  3. Easing cold and allergy symptoms: The promethazine in Stilpane is an antihistamine, which means it helps to relieve allergy symptoms like:
  4. Sneezing & congestion: Stops frequent sneezing, runny nose, and watery eyes.
  5. Helping with respiratory infections: Doctors may prescribe Stilpane for upper respiratory infections. The syrup helps to manage symptoms like cough, pain, and congestion, making it easier for a person to breathe and feel better while the body fights the infection.
  6. Promoting rest and sleep: The ingredients in Stilpane can help make you feel more relaxed and sleepy. This is helpful if you have trouble sleeping because of coughing or other symptoms from a cold or infection.

Important reminders

  • Follow the doctor’s instructions: Always take Stilpane exactly as your doctor tells you.
  • Measure the dose carefully: Use a spoon or cup to measure the right amount.
  • Don’t share your medicine: Never share Stilpane with others, even if they have similar symptoms.
  • Store safely: Keep the syrup in a safe place away from children.

Stilpane cough syrup can help treat these symptoms, but it is essential to use it safely and as prescribed.

5 Side Effects of Stilpane Syrup

Stilpane syrup can help with coughs and pain but can also cause side effects. Here are five side effects you should know about:

1) Drowsiness

One common side effect of Stilpane syrup is feeling very sleepy. This happens because of the promethazine and codeine in the syrup. Drowsiness can make it hard to stay alert and focused.

What to do: Avoid driving, riding a bike, or using heavy machinery when you feel drowsy. Try to rest and let the medication help you sleep and recover.

2) Nausea and vomiting

Stilpane syrup can sometimes upset your stomach, causing nausea and even vomiting. This happens because the medication affects how your stomach and brain work together.

What to do: Taking the medicine with food can help. Eating small, frequent meals and avoiding rich or spicy foods can reduce nausea. If vomiting continues, talk to your doctor.

3) Constipation

Codeine can slow down your digestive system, making it hard to have regular bowel movements. This can lead to constipation, which can be uncomfortable and painful.

What to do: Drink plenty of water and eat high-fiber foods like fruits, vegetables, and whole grains. Staying active with light exercises can also help keep your digestive system moving.

4) Dizziness

Some people feel dizzy or lightheaded when they take Stilpane syrup. This happens because the medicine affects your brain and nervous system.

What to do: Stand up slowly from sitting or lying down to avoid sudden dizziness. Sit or lie down if you feel dizzy to prevent falling. Avoid quick movements and take your time.

5) Allergic reactions

In rare cases, people can have allergic reactions to Stilpane syrup. Signs of an allergic reaction include rash, swelling (especially of the tongue, throat, or face), itching, severe dizziness, and breathing problems.

What to do: If you notice any signs of an allergic reaction, stop taking the medication and get medical help. Allergic reactions can be serious and need immediate attention.

Important tips

  • Tell your doctor: Always inform your doctor about any side effects you experience. They can adjust your dose or suggest ways to manage the side effects.
  • Read the label: Follow the instructions on the packaging carefully to avoid taking too much.
  • Stay hydrated: Drink plenty of water to help manage side effects like constipation and dizziness.
  • Avoid alcohol: Do not drink alcohol while taking Stilpane syrup, as it can make side effects worse.
  • Store safely: Keep Stilpane syrup out of reach of children and store it at room temperature away from light.

Understanding these side effects can help you use Stilpane syrup safely. Always follow your doctor’s advice and let them know if you have any problems with the medication.

The Dangers of Abusing Stilpane Syrup

Abusing Stilpane syrup can lead to many serious health problems both short-term and long-term.

Short-Term Effects of Codeine Abuse

Abusing codeine can cause several immediate problems, such as:

  • Drowsiness: Feeling sleepy and unable to stay awake.
  • Nausea and vomiting: Upset stomach and throwing up.
  • Constipation: Difficulty in having regular bowel movements.
  • Dizziness: Feeling lightheaded and unsteady.
  • Euphoria: Feeling unusually happy, which can lead to more misuse.

Long-Term Consequences of Codeine Abuse

Using codeine for a long time can lead to:

  • Addiction: Needing the drug to feel normal and having trouble stopping its use.
  • Liver damage: Especially if combined with too much paracetamol.
  • Mental health problems: Issues like depression and anxiety.
  • Social problems: Trouble with family, friends, and work.
  • Health problems: Ongoing issues with breathing, heart, and digestion.

Stilpane Syrup Addiction

Addiction in the form of opioid use disorder is another risk of abusing Stilpane syrup. Ongoing use of opioids can lead to physical dependence, where the body needs the drug to feel normal. Over time, people may require higher doses to get the same effects, leading to a cycle of abuse.

Addiction can also harm a person’s health and well-being. It can damage relationships, cause money problems, and make it hard to do everyday activities. In severe cases, addiction can even lead to overdose and death.

Stilpane Syrup Overdose

One of the main risks of cough syrup abuse is overdose. Codeine is an opioid that can slow heart rate and breathing when taken in large doses. This can lead to unconsciousness, coma, or even death if not treated immediately.

Stilpane Syrup Addiction Treatment & Recovery

If someone gets addicted to Stilpane syrup, they need help to recover. Treatment includes:

  • Detox: Safely stopping the drug while managing withdrawal symptoms.
  • Therapy: Talking to counselors and joining group sessions to understand and overcome addiction.
  • Medications: Using other medicines to help reduce cravings and withdrawal effects.
  • Support: Having a support system of family and friends.
  • Aftercare: Continuing care after treatment to stay drug-free.

Beyond Addiction Treatment: Addressing Codeine Issues

To stop codeine problems, we need to:

  • Educate: Teach people about the risks of codeine.
  • Monitor prescriptions: Ensure doctors prescribe codeine carefully.
  • Support programs: Help people find healthy ways to deal with pain and stress.

Regulatory Measures

Laws and rules can help control codeine use. This includes:

  • Prescription limits: Setting limits on how much codeine doctors can prescribe.
  • Pharmacy rules: Making sure pharmacies track and report codeine sales.
  • Public campaigns: Informing the public about the dangers of codeine abuse.

The Role of Healthcare Professionals

Doctors, nurses, and pharmacists can help prevent codeine misuse by:

  • Monitoring use: Keeping track of how much codeine patients use.
  • Educating people: Teaching patients about safe use and risks.
  • Spotting abuse: Identifying signs of misuse early and offering help.

Community Awareness

Communities can fight codeine abuse by:

  • Educational programs: Teaching kids and adults about drug safety.
  • Support groups: Offering groups where people can share experiences and get support.
  • Public announcements: Using media to spread awareness about the dangers of codeine abuse.
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Get Treatment for Drug & Alcohol Addiction at Gratitude Lodge

When you’re ready to move beyond addiction to cough syrup or any other addictive substance, reach out to Gratitude Lodge in Southern California. We have welcoming, pet-friendly treatment centers in Newport Beach and Long Beach, CA, and we’re happy to accept health insurance for addiction treatment.

Our supervised detox programs let you withdraw from cough syrup with access to medications, emotional care, and 24/7 clinical supervision. This makes detox safer and more comfortable, preparing you for ongoing inpatient treatment at Gratitude Lodge.

You will get personalized treatment during your stay at Gratitude Lodge. Therapies include:

  • Medication-assisted treatment
  • Psychotherapy
  • Family therapy
  • Group therapy
  • Counseling
  • Holistic treatment
  • Aftercare

Call our friendly team for immediate assistance at 844-576-0144.

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Jenni Bussi

Jenni Busse MS, LPCC

Jenni Busse MS, LPSS is the Clinical Director at Gratitude Lodge. Jenni oversees the clinical program and the clinical team at Gratitude Lodge as a whole. Jenni has worked in treatment for almost 14 years. Her background as a licensed therapist and her passion for helping others intersected with addiction recovery when she started working primarily in detox residential treatment.
Joe Gilmore

Joseph Gilmore

Joseph Gilmore has been working in the addiction industry for half a decade and has been writing about addiction and substance abuse treatment during that time. He has experience working for facilities all across the country. Connect with Joe on LinkedIn.

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