An SSRI (selective serotonin reuptake inhibitor) is a type of antidepressant medication that’s approved by FDA (U.S. Food and Drug Administration) to treat conditions like depression, anxiety, and bulimia nervosa. SSRI medication works by maintaining the activity of neurotransmitters – chemical messengers – in the brain.

What Are SSRI Medications?

SSRIs are a first-line treatment option for depression due to their general effectiveness and relative lack of side effects compared to other treatments.

This class of medication works by boosting serotonin levels in the brain. Serotonin, a neurotransmitter known for promoting well-being and relaxation, circulates in the brain before being reabsorbed. Depression has been associated with reduced serotonin levels.

By inhibiting serotonin reabsorption, SSRIs ensure that a higher concentration of this feel-good neurotransmitter remains active in the brain, helping alleviate depressive symptoms. Importantly, SSRIs do not increase serotonin production but instead make existing serotonin more available by slowing its reabsorption.

Commonly prescribed SSRIs include:

• Citalopram (Celexa)
• Escitalopram (Lexapro)
• Fluoxetine (Prozac)
• Fluvoxamine (Luvox)
• Paroxetine (Paxil)
• Sertraline (Zoloft)

Each of these medications can be used in combination with talk therapies to treat depression and other mental health conditions.

SSRI Withdrawal Symptoms

SSRI withdrawal is clinically described as antidepressant discontinuation syndrome. This may occur when someone who has been using SSRIs for six weeks or more discontinues use. The risk increases if the medication is stopped abruptly rather than tapered under medical supervision.

Withdrawal symptoms include insomnia, nausea, and flu-like symptoms, usually subsiding within two months. Although SSRI withdrawal is not physically dangerous, it can be highly uncomfortable. Discontinuing an antidepressant may also cause a return of the original condition it was prescribed for, such as depression or anxiety.

Consult with a healthcare provider before stopping any antidepressant to avoid or minimize withdrawal effects.

SSRI Side Effects

SSRIs are known for their specificity in targeting serotonin with minimal effects on dopamine and norepinephrine, resulting in fewer side effects than TCAs or MAOIs.

Common SSRI side effects include:

• Decreased libido
• Sexual dysfunction
• Sleep issues
• Changes in weight
• Anxiety
• Dizziness
• Dry mouth
• Headaches
• Gastrointestinal disturbances

FDA has issued a warning about an increased risk of suicidal thoughts and behaviors in children and young adults taking SSRIs and other antidepressants.

Dependence on SSRIs

SSRIs are not considered addictive because they do not produce cravings or compulsive drug-seeking behavior. That said, long-term use may lead to physical dependence, meaning withdrawal symptoms can occur if the medication is suddenly stopped.

Tapering under medical supervision is the safest way to discontinue SSRIs.

FAQs

Are SSRIs Addictive?

SSRIs are not considered addictive because they do not cause cravings or compulsive use. However, sudden discontinuation can trigger withdrawal symptoms due to physical dependence.

Is Wellbutrin an SSRI?

Wellbutrin is not an SSRI. It is an NDRI (norepinephrine-dopamine reuptake inhibitor).

Is Lexapro an SSRI?

Yes. Lexapro (escitalopram) is an SSRI commonly prescribed for depression and anxiety.

Is Zoloft an SSRI?

Yes. Zoloft (sertraline) is an SSRI used for depression, anxiety disorders, OCD, panic attacks, and more.

Get Treatment for Prescription Drug Dependence at Gratitude Lodge

If you have developed dependence on SSRIs or other prescription medications, begin your recovery at Gratitude Lodge in Newport Beach or Long Beach, California.

Most people benefit from supervised detoxification and a tapered reduction in dosage. Choose medical detox at Gratitude Lodge to ease withdrawal and transition smoothly into inpatient treatment.

All prescription drug addictions are unique. Expect a personalized blend of treatments such as:

• Medication-assisted treatment
• Psychotherapies
• Motivational therapies
• One-to-one counseling
• Group therapy
• Family therapy
• Holistic therapies
• Aftercare

Call 844-576-0144 today and begin your recovery from SSRI dependence.

Sources

1. https://www.ncbi.nlm.nih.gov/books/NBK554406/
2. https://www.health.harvard.edu/mind-and-mood/serotonin-the-natural-mood-booster
3. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449237/
4. https://www.ncbi.nlm.nih.gov/books/NBK430931/
5. https://www.ncbi.nlm.nih.gov/books/NBK539848/
6. https://www.fda.gov/drugs/postmarket-drug-safety-information-patients-and-providers/suicidality-children-and-adolescents-being-treated-antidepressant-medications