Cocaine is a strong stimulant that affects the brain quickly. How long does cocaine stay in your system after using it, though?

This guide will help you understand the immediate effects of cocaine and how long its effects last in the body. Knowing this information can be helpful for drug tests and for becoming aware of how cocaine impacts your health. You can also discover how to get effective cocaine addiction treatment.

What Are the Immediate Effects of Cocaine?

Cocaine acts very fast and makes people feel energetic and happy. This feeling, called a high, can happen just a few minutes after taking the drug. People may also feel more alert and confident. But cocaine can also cause bad effects like being nervous, having a high heart rate, or feeling sick. These effects can be dangerous, especially if someone takes too much of the drug.

How Long Do the Effects of Cocaine Last?

The high from cocaine does not last long. If someone snorts cocaine, the high can last from 15 to 30 minutes. If they smoke or inject it, the high might only last 5 to 10 minutes. Because the high is short, people often take more cocaine to keep feeling the effects. This often leads to addiction and other serious health problems.

How Is Cocaine Metabolized in the Body?

When someone takes cocaine, their body starts to break it down quickly. The liver and blood [1] are responsible for metabolizing the substance. Enzymes in the liver turn cocaine into substances called metabolites. The main metabolite is benzoylecgonine [2]. This process happens fast, but the metabolites can stay in the body for a while. These metabolites are what drug tests usually look for.

When cocaine enters the body, it affects the central nervous system [3], leading to the intense high that people feel when using the drug. This happens because cocaine blocks the reabsorption of dopamine, a neurotransmitter that helps control pleasure and movement. By blocking dopamine reabsorption, cocaine causes an accumulation of dopamine in the brain, leading to increased feelings of euphoria and energy.

The metabolism of cocaine involves several steps:

• Absorption: Cocaine can be absorbed through different methods such as snorting, smoking, injecting, or ingesting. How it’s used affects how quickly cocaine enters the bloodstream. Smoking or injecting cocaine causes it to enter the bloodstream almost immediately, leading to a rapid and intense high. Snorting or ingesting cocaine results in a slower absorption rate.

• Distribution: Once in the bloodstream, cocaine is distributed throughout the body. It crosses the blood-brain barrier quickly, which is why its effects on the brain are felt so rapidly.

• Metabolism: Enzymes found in the blood and liver and blood metabolize cocaine. The main enzymes involved are BChE  and hCE1 [4,5]. These enzymes break down cocaine into two main metabolites: benzoylecgonine and ecgonine methyl ester. Benzoylecgonine is the main metabolite looked for in drug tests because it remains in the body longer than cocaine itself.

• Excretion: Cocaine and its metabolites are excreted from the body primarily through urine. Smaller amounts are also excreted in sweat, saliva, and hair. The rate at which cocaine is eliminated can vary based on factors like the person’s metabolic rate, how much cocaine was used, and how frequently it is used.

How Long Does Coke Stay in Your System?

How coke stays in the system depends on many variables, such as how much you used, how often you used it, and your body’s metabolism. Different tests can detect cocaine or its metabolites for varying periods.

How Long Does Cocaine Stay in Urine?

Urine tests are most commonly used to check for cocaine in the system. After using cocaine, it may be found in your urine for about 3 or 4 days. However, if you use cocaine often or in large amounts, it could be found in your urine for up to a week or more. The urine test looks for benzoylecgonine, a substance your body makes when it breaks down the drug.

How Long Does Cocaine Stay in Your Body?

Different parts of your body can hold onto cocaine or its metabolites for different amounts of time. Here’s a quick guide:

• Blood: 1 or 2 days

• Saliva: 1 or 2 days

• Urine: 3 or 4 days

• Hair: 90 days or more

These time frames can vary based on individual factors like metabolism, body fat, and overall health.

How Long Does Cocaine Stay in Your Blood?

If you’re wondering how long does cocaine stay in your bloodstream, blood tests can show cocaine use for a shorter time than urine tests. Cocaine can be found in your blood for just 1 or 2 days. Blood tests are less common because cocaine leaves the blood quickly, but they are sometimes used in emergency situations to determine recent use.

How Long Does Cocaine Stay in Saliva?

Saliva tests can also detect cocaine use, but like blood tests, they have a shorter detection window. Cocaine can be found in saliva for about 1 or 2 days. A saliva test is simple to use and less invasive, but this test is not as commonly used as a urine test.

Knowing how long cocaine stays in your system is beneficial, especially if you are facing a drug test or concerned about your health. If you or someone you know is abusing this dangerous drug, seeking help can lead to long-term recovery and a healthier and happier life.

How Long Does Cocaine Stay in Your System for a Drug Test?

Drug tests can find cocaine in your body for different amounts of time according to the test used. Here’s a breakdown of how long cocaine is detectable with different tests:

• Urine test: This is the most common test. Cocaine may be found in urine for about 3 or 4 days. With heavy use, it can be found for a week or more.

• Blood test: Cocaine stays in the blood for a shorter time, usually 1 or 2 days.

• Saliva test: Cocaine remains in saliva for about 1 or 2 days.

• Hair test: This test can find cocaine for the longest time. Cocaine can be found in hair for 90 days.

Knowing how long does cocaine stay in your system for a drug test can help you understand the risks of drug use and the importance of avoiding substance use, especially if you have a drug test coming up.

Cocaine Half-Life

For cocaine, the half-life is about 1.5 hours. This means that in 1.5 hours, 50% of the cocaine you used is gone from your bloodstream. It takes about five half lives for cocaine to be eliminate completely from the system. However, the body also makes metabolites like benzoylecgonine, which have a longer half-life of about 6 hours. This is why drug tests look for these metabolites instead of cocaine itself.

 How Long Does It Take to Get Cocaine Out of Your System?

Eliminating cocaine from the system depends on several factors, such as how much you used, how often you used it, and your metabolism. Here are some tips to help your body clear cocaine more quickly:

• Hydrate: Drinking lots of water can help flush out toxins.

• Exercise: Physical activity can boost your metabolism and help your body get rid of cocaine faster.

• Healthy diet: Eating nutritious foods can support your body’s natural detox processes.

• Sleep: Getting plenty of rest allows your body to heal and recover.

It usually takes about 3 to 4 days for cocaine to leave your urine, 1 or 2 days for your blood and saliva, and 90 days in the hair. If you are worried about cocaine in your system, the best thing to do is to stop using it and seek help if you need it. Recovery is possible, and many resources are available to support you.

What Factors Affect How Long Cocaine Stays in Your System?

Several variables can impact how long it takes for cocaine to be metabolized and excreted from the body. Here are some key factors that can affect this process:

• Amount used: The body takes longer to eliminate large doses of cocaine.

• Frequency: With frequent use, cocaine can build up in your body. This is because each dose of cocaine adds to the amount already in your system, making it harder for your body to eliminate it completely. People who use cocaine regularly may find that it takes longer for the drug to leave their system than someone who uses it only once in a while.

• Method of use: The way you take cocaine can also play a part in how long it stays in your system. When you snort cocaine, it enters your bloodstream through the nasal tissues. This method usually leads to a slower onset of effects, but the drug may stay in your system longer. How long does crack stay in your system? Smoking cocaine gets it into your bloodstream quickly through your lungs. This method results in a rapid and intense high, but the drug may leave your system faster. Injecting cocaine delivers it directly into your bloodstream. This method provides an immediate and powerful high, but like smoking, the drug may be metabolized and excreted more quickly.

• Body fat and metabolism: Your body composition and metabolic rate can affect how long cocaine remains in the system. People with higher body fat may retain cocaine and its metabolites longer because these substances can be stored in fatty tissues [5]. Additionally, people with a faster metabolism may process and eliminate cocaine quicker than those with a slower metabolism.

• Age and health: Age and overall health can also play a part in how long cocaine stays in your system. Younger people generally have faster metabolisms and may process drugs quicker than older adults. Beyond this, if you have health issues – especially related to your liver or kidneys – it may take longer for your body to break down and eliminate cocaine.

• Hydration and diet: Staying hydrated and eating a healthy diet can help your body process and eliminate cocaine more efficiently. Drinking plenty of water helps flush out toxins through urine, while a balanced diet provides the nutrients your body needs to function properly.

• Polydrug use: Using cocaine with other substances can affect how long it stays in your system. For example, combining cocaine with alcohol creates cocaethylene [6], a substance which is more toxic and stays in your body longer than cocaine. This can complicate the elimination process and extend the time cocaine and its metabolites are detectable.

• Individual differences: Each person’s body is unique, and individual differences can affect how long cocaine stays in your system. Factors like genetics, overall health, and lifestyle choices can all impact the metabolism and excretion of cocaine. 

What Other Substances Make You Test Positive for Cocaine?

While a false positive for cocaine on a urine drug screen is rare, it can happen – research [7] suggests that 5% to 10% of all drug tests might give false positives, and 10% to 15% might give false negatives. This can cause significant problems for the person being tested. If you think this has happened, follow up with your doctor or the person who ordered the test. They can verify the result using more specific tests, like GC-MS or LC-MS/MS [8,9]. GC-MS is considered the gold standard for drug testing because it reduces the chance of a false positive to almost zero. However, if the GC-MS column isn’t set up to find all possible substances, there is a small chance of a false negative.

Benzoylecgonine is the main metabolite of cocaine and is very specific for cocaine on a drug screen. Some people might claim they used substances like procaine or lidocaine, which are similar but not the same. However, benzoylecgonine specifically indicates cocaine or coca tea use. This makes it a reliable marker in drug testing.

Get Treatment for Cocaine Addiction at Gratitude Lodge

If you or a loved one are struggling with cocaine addiction, contact Gratitude Lodge. We have pet-friendly rehabs by the beach in Southern California where you can access immersive inpatient treatment.

Although there are no FDA-approved medications to treat cocaine withdrawal and addiction, supervised detox makes the withdrawal process safer and easier, and it also helps you transition to ongoing treatment at our Long Beach or Newport Beach rehabs.

Since every cocaine addiction is unique, you can expect to access personalized therapies that include:

• Motivational therapy
• Talk therapy
• Counseling
• Family therapy
• MAT (medication-assisted treatment)
• Holistic therapies
• Group therapy
• Aftercare

Begin your recovery from cocaine addiction by calling 844-576-0144.

Sources

[1] https://www.ncbi.nlm.nih.gov/books/NBK548454/

[2] https://pubchem.ncbi.nlm.nih.gov/compound/Benzoylecgonine

[3]https://pubmed.ncbi.nlm.nih.gov/8314357/

[4]https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/butyrylcholinesterase

[5]https://pubmed.ncbi.nlm.nih.gov/10802199/

[6] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956485/

[7] https://www.rttnews.com/amp/1323040/new-study-shows-inconsistencies-in-drug-testing.aspx

[8] https://www.acs.org/education/whatischemistry/landmarks/gas-chromatography-mass-spectrometry.html

[9] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2643089/