Amphetamine Salts vs Dextroamphetamine

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Updated March 3, 2025

Authored By:

Joe Gilmore

Edited By

Amy Leifeste

Medically Reviewed By

Javier Rodriguez-Winter

Authored By:

Joe Gilmore

Edited By

Amy Leifeste

Medically Reviewed By

Javier Rodriguez-Winter

psychiatry session representing trazodone and alcohol

Amphetamine salts and dextroamphetamine are both stimulant medications, often used to treat ADHD and narcolepsy, but they have some differences in composition and effects.

These two drugs have similar side effects and risks. However, there are also some important differences between Dexedrine and Adderall.

This guide to amphetamine salts vs dextroamphetamine highlights the similarities and difference between these two stimulant medications. You can also learn how to connect with compassionate and effective addiction treatment.

 

What Are Amphetamine Salts?

Amphetamine salts are a mix of different types of amphetamine, typically including both dextroamphetamine and levoamphetamine. They are used in medications like Adderall to help treat ADHD and narcolepsy. 

The term “salts” refers to the chemical structure of the drug, which helps the body absorb and process it more effectively. Common medications that contain amphetamine salts include Adderall and its generic versions. 

These medications work by increasing the levels of certain neurotransmitters in the brain, helping to improve focus and control behavior in individuals with ADHD.

 

Uses of Amphetamine Salts

Amphetamine is a medicine that helps people stay awake and focused. It can also help control behavior. It’s used to treat the following conditions:

  • ADHD: Amphetamine is often used to help people with ADHD focus better and be less hyperactive.

  • Narcolepsy: It helps people with narcolepsy stay awake during the day.

  • Off-label uses: Amphetamine salts may be used off-label (not officially approved by the FDA for these uses) for other conditions, though this should only be done under medical supervision

 

Amphetamine Dosages

Dosages of amphetamines depend on the type of medication, whether it’s immediate-release or extended-release, and the person’s age, weight, and how they respond to the drug. It’s essential to follow the doctor’s instructions for taking these medications. 

 

 

What Is Dextroamphetamine?

Dextroamphetamine, also called Dexedrine, is a medication that helps the brain with hyperactivity and impulse control. It’s a CNS (central nervous system) stimulant. ADHD makes it hard for people to stay focused, control their impulses, and not be too hyper. Besides using therapy and other treatments, many people with ADHD take medications like dextroamphetamine to manage their symptoms.

Types of dextroamphetamines include:

  • Immediate-release tablets: Adults usually start with 5mg once or twice a day. The dose can be changed based on how well it works.
  • Extended-release capsules: With d-amphetamine dr, adults typically start with 10mg once a day in the morning.
 

Uses of Dexedrine / Dextroamphetamine

This medication is used to treat the following conditions:

  • Treating ADHD: Dexedrine/dextroamphetamine helps people with ADHD by improving focus and reducing hyperactivity and impulsiveness.
  • Treating narcolepsy: It is also used to help people with narcolepsy stay awake during the day.
  • Off-label uses: Sometimes, doctors might prescribe it for other conditions, but always follow your doctor’s advice on how to use it safely.

 

Dosages of Dextroamphetamine

The amount of dextroamphetamine you need depends on the type of medication, the condition being treated, and your age, weight, and response to the medicine. Always follow the doctor’s instructions. 

 

Differences Between Amphetamine Salts and Dextroamphetamine

While amphetamine salts and dextroamphetamine have similarities in treatment for ADHD and narcolepsy, their key differences lie in their chemical composition, potency, and side effects. 

Amphetamine salts are a combination drug that provides a broader range of effects, while dextroamphetamine is a purer stimulant that may have stronger but more targeted effects. 

The choice between them typically depends on an individual’s response and their medical needs. Your prescribing doctor will help you understand which drug is best for you based on your individual needs. 

 

Differences in Dosages, Uses, & Chemical Makeup

These substances differ in the following ways:

 

Dosage Differences

  • Amphetamine salts (Adderall): The typical starting dose for immediate release is 5mg once or twice daily. Extended release usually starts at 20mg once daily.
  • Dextroamphetamine (Dexedrine): The typical starting dose for immediate release is 5mg once or twice daily. Extended-release usually starts at 10mg once daily.

 

Use Differences

  • Both: Used to treat ADHD and sometimes narcolepsy.
  • Amphetamine salts: Can also be used for short-term weight loss.

 

Chemical Makeup Differences

  • Amphetamine salts: A mix of amphetamine and dextroamphetamine.
  • Dextroamphetamine: Contains only dextroamphetamine, which is a more potent form.

These differences help doctors decide which medication is best for each individual. Always follow the prescribed instructions for safe and effective use.

 

Stimulant Abuse of Amphetamine & Dextroamphetamine

Stimulant abuse happens when someone uses drugs like amphetamine or dextroamphetamine too much or without a doctor’s prescription. These drugs can make you feel very awake and focused, but using them too much is dangerous.

  

Recognizing Signs of Addiction

Look out for the following signs if you or someone you care about is abusing this class of medication:

  • Increased use: Needing more of the drug to feel the same effects.
  • Preoccupation: Spending a lot of time thinking about or trying to get the drug.
  • Loss of control: Finding it hard to stop using the drug, even if you want to.
  • Neglecting responsibilities: Ignoring school, work, or family duties because of drug use.
  • Physical symptoms: Feeling sick, tired, or anxious without the drug.

 

Stimulant Addiction Risk Factors

Many factors influence someone’s risk for addiction. These include:

  • Family history: If your family has a history of addiction, you might be more at risk.
  • Mental health issues: Conditions like depression or anxiety can increase the risk of addiction.
  • Early drug use: Starting drug use at a young age makes addiction more likely.
  • Stress and environment: High stress and being around others who use drugs can also raise the risk.

 

Treatment for Stimulant Abuse

There are many ways to get back on track from stimulant abuse.

  • Therapy: Talking to a therapist can help you understand your addiction and find ways to stop.
  • Group therapy: Offers support from others who are also trying to stop using drugs.
  • Medications: Doctors can prescribe medicines to help manage withdrawal symptoms and cravings.
  • Support groups: Joining a group like NA (Narcotics Anonymous) can provide encouragement and advice from people who understand what you’re going through.
  • Rehab programs: These programs provide a safe place to stay while you get intensive help for your addiction. They offer medical care, therapy, and support.
  • Healthy lifestyle choices: After treatment, it’s important to continue making healthy choices. This can include regular exercise, eating well, avoiding triggers, and staying connected with supportive friends and family.

Getting help is the first step to overcoming addiction and leading a healthier, happier life. If you or someone you know is struggling with stimulant abuse, talk to a doctor or reach out to a local support group.

 

Amphetamine Salts vs Dextroamphetamine | FAQs

 

What is the amphetamine legal classification?

Amphetamines are classified as a Schedule II controlled substance in the United States. This means they have a high potential for abuse but can be used legally with a prescription.

 

What is an amphetamine used for?

Amphetamine is a medicine that helps people stay awake and focused. It can also help control behavior. It’s used to treat the following conditions: ADHD, narcolepsy, and obesity. 

 

What types of amphetamines are there? 

Amphetamines are a type of drug that can make you feel more awake and focused. They are often used to treat ADHD and other conditions. There are three main types of amphetamine: Adderall, Dexedrine, and Vyvanse.

 

What are common brand names for amphetamine salts?

Amphetamine salts are a mix of different types of amphetamines. They are often used in medications to treat ADHD and other conditions. Common brand names include Adderall and Mydayis. 

 

Are Amphetamine and Dextroamphetamine the Same?

No, they are not the same. Amphetamine refers to a group of similar drugs, while dextroamphetamine is a specific type of amphetamine.

 

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Get Treatment for Drug Addiction & Mental Health Disorders at Gratitude Lodge

If you or a loved one needs compassionate and effective treatment for stimulant addiction, contact Gratitude Lodge in Southern California. We have, pet-friendly rehabs in Newport Beach and Long Beach.

Supervised detox at one of our rehabs by the beach provides access to 24/7 care and medications to streamline the stimulant withdrawal process. After a week or so, you will be ready for ongoing inpatient treatment.

All stimulant addictions are unique, so all our treatment programs offer personalized interventions like:

  • Talk therapies
  • MAT (medication-assisted treatment)
  • Family therapy
  • Group therapy
  • Counseling
  • Holistic treatments
  • Aftercare

 

Call our recovery experts at 844-576-0144.

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Jenni Bussi

Jenni Busse MS, LPCC

Jenni Busse MS, LPSS is the Clinical Director at Gratitude Lodge. Jenni oversees the clinical program and the clinical team at Gratitude Lodge as a whole. Jenni has worked in treatment for almost 14 years. Her background as a licensed therapist and her passion for helping others intersected with addiction recovery when she started working primarily in detox residential treatment.
Joe Gilmore

Joseph Gilmore

Joseph Gilmore has been working in the addiction industry for half a decade and has been writing about addiction and substance abuse treatment during that time. He has experience working for facilities all across the country. Connect with Joe on LinkedIn.

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