Dexedrine vs. Adderall: What Are The Differences?

Are Dexedrine & Adderall the Same?

Dexedrine and Adderall are not the same. Even though they both treat ADHD and contain amphetamines, their ingredients and how they work in the body are different. Dexedrine only has dextroamphetamine, while Adderall has a mix of dextroamphetamine and levoamphetamine. These differences can affect how each drug works and its side effects.

Similarities Between Adderall & Dextroamphetamine

Adderall and Dexedrine have many similarities because they both belong to the same class of medications called CNS stimulants. Here are some of the main similarities:

• Purpose: Both medications are mainly used to treat ADHD and narcolepsy. They help improve focus, attention, and control over impulses.

• Mechanism of action: Both Adderall and Dexedrine increase the levels of neurotransmitters like dopamine and norepinephrine in the brain. This helps improve communication between brain cells, enhancing attention and reducing hyperactivity.

• Forms: Both medications come in immediate-release and extended-release forms. Immediate-release forms work quickly, while extended-release forms provide a steady dose throughout the day.

• Side effects: Both medications can cause similar side effects, including dry mouth, loss of appetite, weight loss, insomnia, headaches, and increased heart rate. These side effects occur because both drugs are stimulants and affect the central nervous system in similar ways.

• Dosage: Starting doses for both medications are often similar, with gradual increases based on how well the medication works and how well it is tolerated by the patient. Both medications usually have a maximum daily dose of around 40mg.

Because of these similarities, doctors may choose either medication based on how well a person responds to one over the other. 

Dextroamphetamine vs Adderall Dosage

The dosage for Dexedrine and Adderall depends on age and how well the medication works for the person. Here are general dosage guidelines:

Dexedrine:

• Children aged 3 to 5: Start with 2.5mg per day.

• Children aged 6+ and adults: Start with 5mg once or twice a day. The dose can go up by 5mg each week if needed, but usually not more than 40mg per day.

Adderall:

• Children aged 3 to 5: Start with 2.5mg per day.

• Children aged 6+ and adults: Start with 5mg once or twice a day. The dose can go up by 5mg each week if needed, but usually not more than40 mg per day.

Both medications should be taken in the morning and early afternoon to avoid trouble sleeping.

Dextroamphetamine vs Adderall—Which is Stronger?

Dexedrine is often considered stronger than Adderall because it only has dextroamphetamine, the more potent form of amphetamine. Adderall has a mix of dextroamphetamine and levoamphetamine, which might make it a bit less potent for some people.

Is the D-amphetamine Salt Combo the Same as Adderall?

The D-amphetamine salt combo refers to a combination of amphetamine salts, which is what makes up Adderall. Adderall contains two main ingredients: dextroamphetamine and levoamphetamine. These are types of amphetamine salts that work together to treat ADHD by increasing focus and decreasing impulsive behavior.

• Combination: Adderall is a mix of these two salts in a specific ratio (3:1 of dextroamphetamine to levoamphetamine). This combination helps balance the effects, providing better control over symptoms for many people.

• Forms: Adderall comes in both IR (immediate-release and XR (extended-release) forms. The IR form works quickly, while the XR form releases the medication slowly throughout the day.

• Mechanism: The way Adderall works is by increasing the levels of certain neurotransmitters in the brain, such as dopamine and norepinephrine. This helps improve attention and focus while reducing hyperactivity and impulsive behavior.

Amphetamine Sulfate vs Adderall

Amphetamine sulfate is another type of stimulant used to treat ADHD, but it is different from Adderall. Here are the differences and similarities:

• Ingredients: Amphetamine sulfate contains only one type of amphetamine, while Adderall is a combination of amphetamine salts (dextroamphetamine and levoamphetamine). This makes their chemical compositions different.

• Strength: Adderall might be more effective for some people because it contains both dextroamphetamine and levoamphetamine, which can provide a more balanced effect. Amphetamine sulfate, on the other hand, might be better for those who need a simpler medication.

• Usage: Both medications are used to treat the same conditions – ADHD and narcolepsy. They help improve focus, attention, and control over impulsive behaviors.

• Side effects: Both can cause similar side effects, such as dry mouth, weight loss, trouble sleeping, and headaches. However, the intensity and occurrence of these side effects can vary from person to person.

• Forms: Adderall is available in both immediate-release and extended-release forms, providing flexibility in how it is administered. Amphetamine sulfate is usually available in immediate-release form, but some formulations might offer extended-release options.

Choosing between amphetamine sulfate and Adderall often depends on how a person responds to the medication and their specific needs.

What Is Stronger Than Adderall?

When considering medications for ADHD, some may wonder if there is anything stronger than Adderall. Here are a few options that are sometimes considered stronger:

• Vyvanse (Lisdexamfetamine): Vyvanse is a prodrug, meaning it is inactive until the body converts it into its active form, dextroamphetamine. This process can make Vyvanse last longer and provide a smoother effect, which some consider stronger due to its prolonged action.

• Desoxyn (methamphetamine hydrochloride): Desoxyn is a very powerful stimulant that contains methamphetamine. It is used less frequently due to its high potential for abuse and addiction but is considered very strong.

• Concerta (methylphenidate extended-release): Concerta is another long-acting stimulant that some find stronger because it lasts throughout the day. It contains methylphenidate, which is also found in Ritalin (another common ADHD medication).

• Focalin XR (dexmethylphenidate): This medication is similar to Concerta but contains only the active part of the molecule found in methylphenidate.

Stronger does not always mean better. The best medication is one that effectively manages symptoms with the fewest side effects. Always consult with a healthcare provider to determine the most appropriate treatment.

What Is Better: Dextroamphetamine or Adderall?

Deciding between dextroamphetamine and Adderall can depend on several factors:

• Effectiveness: Both medications are effective in treating ADHD and narcolepsy. Some people may respond better to one medication over the other.

• Side effects: Both medications have similar side effects, such as dry mouth, insomnia, and weight loss. However, some patients may experience fewer side effects with one medication compared to the other.

• Duration: Adderall XR and Dexedrine Spansule are long-acting forms that can last all day, which might be more convenient for some people. Immediate-release forms of both medications require multiple doses throughout the day.

• Personal response: Individual responses to medications can vary. What works well for one person might not work as well for another. It often takes some trial and error to find the best medication and dosage.

• Cost and insurance: The cost of medications and insurance coverage can also play a role in deciding which medication to use. Both Dexedrine and Adderall are available in generic forms, which can be more affordable.

Ultimately, the choice between Dexedrine and Adderall should be made with the help of a healthcare provider, considering the patient’s specific needs and medical history.

Warning Signs of Stimulant Abuse & Addiction

Stimulants like Dexedrine and Adderall can be highly beneficial, but they can also be abused. Here are some warning signs of stimulant abuse and addiction:

• Behavior changes: If someone starts acting very differently, like being more aggressive, anxious, or paranoid, it might be a sign of substance abuse.

• Physical changes: Look for sudden weight loss, red eyes, or a flushed face. These can be signs of stimulant abuse.

• Sleep problems: Trouble sleeping or staying awake at odd times can be a warning sign.

• Neglecting responsibilities: If someone is not taking care of their schoolwork, job, or family, it might be because of drug abuse.

• Financial issues: Constantly asking for money or having unexplained financial problems can be a sign of substance misuse.

• Isolation: Staying away from friends and family or losing interest in activities they used to enjoy can be a sign of addiction.

• Physical symptoms: Look for signs like fast heartbeat, high blood pressure, or unexplained wounds on fingers or toes. These can be serious and need medical attention.

If you or someone you know is showing these signs, get help right away. Stimulant abuse can lead to serious health problems and even be life-threatening. Fortunately, the condition is also highly treatable.

Get Insurance-Covered Treatment for Drug & Alcohol Addiction at Gratitude Lodge

If you have been misusing prescription medications like dextroamphetamine or Adderall, we can help you get back on track at Gratitude Lodge in Southern California. We have welcoming, inclusive rehabs in Long Beach and Newport Beach where you can get immersive inpatient treatment.

When you choose supervised detox at one of our luxury rehabs, withdrawal is safer and more comfortable. You can access medications and 24/7 care as you taper off stimulants and prepare for ongoing treatment.

The unique nature of all stimulant addictions means that all our treatment programs offer personalized therapies, including:

• Talk therapy
• Counseling
• Family therapy
• Group therapy
• Holistic treatments
• Medication-assisted treatment
• Aftercare

Call our recovery experts for immediate assistance at 800-994-2184.