How Long Does Lexapro Stay in Your System?

Updated December 6, 2024

How Long Does Lexapro Stay in Your System?

Lexapro (escitalopram) is an antidepressant that’s used for the treatment of depression and GAD (generalized anxiety disorder. The medication typically stays in your system for six days, although many variables can influence this timeline.

This guide explores how long does Lexapro stay in your system in detail and shows you how to connect with compassionate and effective addiction treatment [1].

What Is Lexapro?

Lexapro is a medicine that doctors prescribe to help with depression or anxiety. It is an SSRI (selective serotonin reuptake inhibitor)[2]. These drugs work by boosting the level of serotonin in your brain, which helps improve your mood.

Lexapro can help with symptoms like:

Feeling very sad for a long time

Losing interest in things you used to enjoy

Worrying a lot

Feeling very nervous

Lexapro usually comes as a pill that you take by mouth. Follow your doctor’s instructions on how much to take and when to take it. Lexapro can be effective for managing depression and anxiety when taken properly under a doctor’s care.

Is Escitalopram the Same as Lexapro?

Escitalopram is the generic version of the branded medication Lexapro. It contains the same ingredients and is used to treat the same conditions.

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How Lexapro Interacts with Your Body & Brain

Lexapro helps you feel better by working on your brain and body. Here’s a closer look at how it does this:

How Lexapro works in the brain

Lexapro increases serotonin levels [3]. Serotonin is a natural chemical in your brain that helps control mood. When serotonin levels are higher, you tend to feel happier and calmer. By balancing serotonin, Lexapro helps stabilize your emotions, making mood swings less intense and helping you feel more even-tempered.

How Lexapro works in the body

Lexapro can help you sleep better by reducing anxiety and calming your mind. A good night’s sleep is essential for feeling good and staying healthy. Lexapro helps calm your body by reducing physical symptoms of anxiety like a racing heart or sweaty palms. This makes you feel more relaxed in stressful situations. By lifting your mood, Lexapro helps you feel less sad and more interested in activities you used to enjoy. This can make daily life feel more manageable and enjoyable.

Controlled Substance Classification

Lexapro is not classified as a controlled substance by the DEA (United States Drug Enforcement Administration). While the medication does not have a high potential for abuse and addiction, it is only available with a prescription in the U.S.

Common Uses of Lexapro

Lexapro is a helpful medication that doctors prescribe for several reasons. Here are some common uses of Lexapro:

Depression

Lexapro is often used to treat depression [4]. It helps improve mood, making you feel happier and more interested in daily activities.

Anxiety disorders

Lexapro can help people who have anxiety disorders [5]. It reduces feelings of worry and helps calm the mind. It can help with the following conditions:

GAD (generalized anxiety disorder): Lexapro is used to treat GAD, a condition where people feel very worried or anxious about many things. It helps reduce this constant worry.

Social anxiety disorder: Lexapro can also help when people feel very nervous or scared in social situations. It helps make social interactions easier.
Panic disorder: People with panic disorder have sudden attacks of intense fear. Lexapro can help reduce the number of these panic attacks.

Lexapro Half-Life: How Long Does Lexapro Last?

The half-life of Lexapro [6] is about 27 to 32 hours. The half-life is the time it takes for half of the drug to leave your body. This means it takes about one to two days for half of a dose of Lexapro to be removed from your system. It takes five half-lives for all of the medication to be eliminated.

How Long Does Lexapro Stay in Your System?

Lexapro generally stays in your system for about six days. If you have questions like “how long does 5mg of Lexapro stay in your system” or “how long does 10mg of Lexapro stay in your system”, this can vary based on the following variables:

Age: Older adults may take longer to process the medication.

Metabolism: People with faster metabolisms will eliminate the drug quicker.

Dosage: Higher doses may stay in the system longer.

Health: Your liver and kidney health can impact how long Lexapro stays in the body.

It might take one to two weeks to start feeling better when you first begin taking Lexapro. It can take up to six to eight weeks to feel the full benefits of the medication. Always follow your doctor’s instructions and continue taking Lexapro even if you don’t feel better right away. If you have questions or concerns about how long Lexapro stays in your system, talk to your doctor.

Lexapro Dosages

Taking the right amount of Lexapro is very important. Your doctor will tell you how much to take. Here are some common dosages for Lexapro:

Starting dose

For adults, the usual starting dose is 10mg once daily. Your doctor might increase this after a while if needed.

Higher dose

Sometimes, doctors may increase the dose to 20mg a day if the starting dose is not enough to help with your symptoms.

Dosage for Kids and teens

For kids aged 12 to 17, the starting dose is usually 10mg once daily. Your doctor will decide if a higher dose is needed.

Dosage for Seniors

Older adults might start with a lower dose, like 5mg a day, to make sure their bodies handle the medication well.

How to Take Lexapro

Pick a time that works best for you, like in the morning or evening, and take your medicine at the same time every day. You can take Lexapro with food or on an empty stomach. If it upsets your stomach, try taking it with a meal. Take the pill with a glass of water. Do not crush or chew it. Always take the amount your doctor tells you. Never stop using Lexapro without talking to your doctor. They will help you reduce the dose slowly to avoid withdrawal symptoms [7].

How to Store & Dispose of Lexapro

When storing Lexapro:

Keep it cool: Store Lexapro at room temperature, away from moisture and heat. Don’t keep it in the bathroom, where it can get damp.

Safe spot: Put the medication in a place where children and pets cannot reach it. A locked cabinet is best.

Original container: Always keep Lexapro in its original container with the label so you can easily identify it.

When disposing of Lexapro:

Follow instructions: Check the medication label or ask your pharmacist for specific disposal instructions.

Take-back programs: Many places have take-back programs or events where you can safely return unused medications.

Do not flush: Unless the label specifically says it’s okay, do not flush Lexapro down the toilet.

Trash method: If you must throw it away, mix the medication with something unpleasant, like used coffee grounds or cat litter. Then, place it in a sealed bag before putting it in the trash.

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Risks of Taking Lexapro

While Lexapro can help with depression and anxiety, it comes with certain risks. It’s important to understand these risks and discuss them with your doctor.

Increased suicidal thoughts: Some people, especially young adults and teenagers, might have increased thoughts of suicide when they first start taking Lexapro. Always report any unusual mood changes to your doctor.

Allergic reactions: Although rare, some people might have allergic reactions to Lexapro. Signs include rash, itching, swelling, severe dizziness, or trouble breathing. Seek medical help right away if these occur.

Serotonin syndrome: This is a rare but serious condition that can happen if Lexapro is taken with other medications that increase serotonin. Symptoms include hallucinations, rapid heartbeat, dizziness, severe nausea, and muscle twitching.

Short-Term Side Effects of Escitalopram (Lexapro)

When you start taking Lexapro, your body may need time to adjust. During this period, you might experience:

Nausea: Feeling sick to your stomach is common, but usually gets better as your body adjusts.

Tiredness: You might feel more tired than usual.

Sleep problems: Some people have trouble sleeping or feel very sleepy during the day.

Dizziness: Feeling lightheaded can happen, especially when you stand up quickly.

Dry mouth: Your mouth might feel dry. Drinking water and chewing sugar-free gum can help.

These side effects often lessen after a few weeks. If they don’t go away or become severe, contact your doctor.

Long-Term Side Effects of Escitalopram (Lexapro)

Taking Lexapro for a long time can lead to other side effects, which you should discuss with your doctor:

Weight gain: Some people may gain weight over time.

Sexual side effects: Issues like reduced sexual desire or difficulty reaching orgasm can occur.

Mood changes: Rarely, people might experience new or worsening mood changes.

Restlessness: A feeling of being unable to sit still, known as akathisia, can occur in some cases.

Your doctor can help manage these side effects, possibly by adjusting your dose or suggesting lifestyle changes.

Withdrawal Symptoms of Lexapro

Stopping Lexapro suddenly can cause withdrawal symptoms. To avoid these, your doctor will help you taper off the medication slowly. Possible withdrawal symptoms include:

Dizziness: Feeling unsteady or lightheaded.

Headaches: Pain in your head that can vary from mild to severe.

Mood changes: Feeling very sad, anxious, or irritable.

Sleep problems: Difficulty falling asleep or staying asleep.

Flu-like symptoms: Feeling achy, tired, or experiencing chills.

Always follow your doctor’s instructions when stopping Lexapro to minimize these symptoms.

How Lexapro Interacts with Alcohol & Other Pills

Be careful about what you consume when taking Lexapro:

Alcohol: Drinking alcohol while on Lexapro can increase drowsiness and dizziness. It can also worsen depression and anxiety symptoms. It’s best to avoid alcohol.

Other medications: Lexapro can interact with other drugs, which can be dangerous. Always tell your doctor about all other medications, supplements, or vitamins you are taking. This includes over-the-counter drugs.

Blood thinners: Lexapro can increase the risk of bleeding when taken with blood thinners like aspirin or warfarin.

Other antidepressants: Combining Lexapro with other antidepressants or medications that affect serotonin can lead to serotonin syndrome, a serious condition.

Addiction Risk Factors

While Lexapro is not addictive in the same way as drugs like opioids or benzodiazepines, there are still important considerations:

Dependence: Your body can become dependent on Lexapro. If you stop taking it suddenly, you might experience withdrawal symptoms.

Tolerance: Over time, your body might get used to Lexapro, and it may not work as well. This is why it’s important to follow your doctor’s dosing instructions and discuss any changes in how you feel.

Misuse: Taking Lexapro in higher doses than prescribed or using it without a prescription is dangerous and can lead to serious health problems.

Always use Lexapro as directed by your doctor to reduce these risks and ensure it helps you effectively manage your symptoms.

Lexapro & Anti-Depressants | FAQs

What are some side effects of Lexapro?

Some side effects of Lexapro include nausea, tiredness, and trouble sleeping. You might also feel dizzy or have a dry mouth. If side effects bother you, talk to your doctor.

Can I get addicted to antidepressants?

Antidepressants are not addictive like some drugs, but your body can get used to them. It’s important to follow your doctor’s instructions.

What if my Lexapro stops working?

If Lexapro stops working, talk to your doctor. They may adjust your dose or try a different medication. Do not stop taking it without asking your doctor first.

How can I safely stop using Lexapro?

To safely stop using Lexapro, your doctor will help you slowly lower the dose. This helps prevent withdrawal symptoms. Never stop suddenly on your own.

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