Mixing Benadryl & Alcohol

An image representing Is Mixing Benadryl and Alcohol Dangerous?

Updated December 3, 2024

Authored By:

Joe Gilmore

Edited By

Amy Leifeste

Medically Reviewed By

Javier Rodriguez-Winter

Authored By:

Joe Gilmore

Edited By

Amy Leifeste

Medically Reviewed By

Javier Rodriguez-Winter

An image representing Is Mixing Benadryl and Alcohol Dangerous?

Mixing Benadryl & Alcohol

Mixing Benadryl and alcohol is inadvisable and potentially dangerous, as the two substances can interact with each other and have adverse effects [1].

Benadryl is a branded form of diphenhydramine, an antihistamine used to treat allergy symptoms such as coughs, sore throats, and rashes [2].

Alcohol and Benadryl are both classified as CNS depressants. If you take Benadryl in isolation, the medication will not impact your liver directly. Taking Benadryl with alcohol, on the other hand, may increase the intensity of side effects, sometimes provoking serious adverse outcomes.

Today’s guide explores the following topics:

  • Does alcohol affect Benadryl?
  • What happens when you take Benadryl and drink alcohol?
  • Is Benadryl and alcohol dangerous?

You will also discover how to connect with treatment if you develop an addiction to alcohol or prescription medications.

What happens when you take Benadryl with alcohol, then?

Can You Mix Benadryl and Alcohol?

If you take Benadryl with alcohol, both substances work on your CNS (central nervous system). The central nervous system consists of the brain and spinal cord. Alcohol and Benadryl slow the CNS. If you combine alcohol with Benadryl, this can trigger the following alcohol and Benadryl side effects:

  • Drowsiness and sedation
  • Problems with focus
  • Difficulty performing physical tasks

Combining Benadryl with alcohol is never advisable, but it can be especially dangerous for seniors to drink on Benadryl.

If you consume alcohol while taking Benadryl, you should not drive or operate machinery.

If you unintentionally mix alcohol and diphenhydramine, rest in a safe environment to restore balance.

Drinking on Benadryl

When it comes to mixing alcohol and diphenhydramine (commonly known as Benadryl), the potential risks should not be taken lightly. This is because both substances can have a depressing effect on the central nervous system, potentially bringing about severe side effects. In particular, the slowing down of essential functions like respiration can occur when the CNS is depressed, and pairing alcohol with Benadryl can heighten the sedative effect, leading to extreme CNS sedation [3].

Beyond this, both alcohol and Benadryl are known to have dehydrating effects on the body [4]. When the two substances are combined, the risk of dehydration increases, which can lead to discomfort and inflame any hangover experienced the following day.

While both alcohol and Benadryl are capable of causing sedation and drowsiness, it’s unwise to rely on these properties as a sleep aid. Attempting to do so can have adverse side effects that are detrimental to sleep, including dizziness and nausea. This means that it’s crucial to be mindful of the risks involved with alcohol and Benadryl side effects, and avoid combining alcohol and Benadryl without first consulting a healthcare professional.

Can You Drink Alcohol While Taking Antihistamines?

So, can you take allergy medicine with alcohol at all?

No, it is not recommended to mix an antihistamine and alcohol. Particularly if the drug causes drowsiness, combining the two can make you feel extremely sleepy. This is especially unsafe when operating heavy machinery, at work, or during other situations where you need to remain alert. Combining these two substances can also result in dehydration.

Mixing Benadryl and Wine

Wine is a popular alcoholic beverage that is often enjoyed with meals or as a social drink. However, when combined with Benadryl, the risks of adverse effects increase.

The sedative effects of Benadryl can be enhanced when mixed with wine, leading to increased drowsiness, dizziness, and impaired coordination. The combination of alcohol and Benadryl can also provoke memory impairment and a higher risk of falls and accidents.

Additionally, wine can dehydrate the body. When combined with Benadryl, the risk of dehydration increases significantly. Dehydration can cause discomfort, headaches, and loss of concentration. It can also worsen the side effects of Benadryl and alcohol, leading to a more severe hangover the next day.

If you choose to consume wine and Benadryl together, it’s essential to be aware of the risks involved and limit your intake. You should also avoid operating heavy machinery or driving after mixing wine and Benadryl, as the combination can impair your coordination and reaction time. It’s always best to consult with a medical professional before combining any medications or substances, including Benadryl and wine.

Mixing Benadryl and Beer

For some people, blending Benadryl and beer is a concern if they are going to be drinking beer while sick.

However, combining Benadryl and beer can have serious and potentially dangerous consequences. Some of the most common consequences include increased drowsiness, impaired motor skills and coordination, cognitive impairment, increased heart rate and blood pressure, and more.

Blending Benadryl and beer can intensify their individual effects and lead to a variety of adverse reactions, so it is not advisable to take Benadryl while drinking beer.

In fact, alcohol can be inflammatory and it’s always best to rest and restrict alcohol use while you are fighting a virus.

Mixing Claritin and Alcohol

Claritin is an over-the-counter antihistamine that can have mild sedative effects. When combined with alcohol, these effects can be exacerbated, causing intensified drowsiness, dizziness, impaired judgment, and slower reaction times. While combining them may not create serious physical reactions, there is an increased risk of accidents or making poor judgments. Alcohol can also worsen allergy symptoms which counteracts the symptoms that Claritin is used to treat.

For these reasons, it’s not advised to take Claritin and alcohol together.

Mixing Zyrtec and Alcohol

Can you take Zyrtex with alcohol? Zyrtec is a common antihistamine that is used to treat symptoms of allergies. Like other antihistamines, drinking alcohol while on Zyrtec can cause a heightened sense of sleepiness, dizziness, and cognitive function. If you need to do day-to-day activities that require alertness, like driving, work, or childcare, combining alcohol and Zyrtec is much more dangerous than just drinking alcohol alone. If you’re unsure about how Zyrtec and alcohol may interact for you, it’s best to speak with your doctor.

Are Benadryl and Alcohol Dangerous to Mix?

Both Benadryl and alcohol share the ability to suppress the central nervous system (CNS), which can have harmful consequences. The combined sedative effect may cause a drop in heart rate and slow breathing, potentially leading to heart problems or even loss of consciousness. In rare cases, CNS depression can even result in a coma or Benadryl and alcohol death.

Losing consciousness is a common risk associated with mixing alcohol and Benadryl, but there are other health hazards to consider as well. It’s important to be aware of the potential dangers and consult a healthcare provider before combining any medications or substances.

Dangers of Mixing Benadryl and Alcohol

Blending Benadryl and alcohol can lead to a potent sedative effect, increasing the risk of accidents, falls, and difficulty performing daily tasks. The combination can also dehydrate the body, potentially worsening hangovers and causing discomfort and lack of concentration.

Furthermore, long-term use of alcohol and anticholinergic drugs such as Benadryl has been linked to an increased risk of dementia. Blending Benadryl and alcohol, both of which can impair memory and learning, may have a more pronounced impact on cognitive functions.

Older adults should be particularly cautious, as the aging process reduces the body’s ability to break down alcohol. Additionally, using Benadryl with other prescription drugs can produce harmful effects, especially when combined with alcohol.

The sedative alcohol and Benadryl side effects of both substances can also disrupt normal sleeping patterns, causing excessive sleepiness, lethargy, nausea, and dizziness.

Alcohol Addiction and Benadryl

Alcohol addiction is a serious problem affecting millions of people worldwide, with approximately 29.5 million adults in the United States aged 18 and older experiencing alcohol use disorder (AUD) in 2021, according to NIAAA (National Institute on Alcohol Abuse and Alcoholism).

The risks of addiction and overdose increase significantly when alcohol is combined with Benadryl. Benadryl’s sedative effect as a sleep aid can enhance the effects of alcohol, leading to more significant intoxication and potentially causing individuals to develop a dependence on both substances.

Individuals with a history of alcohol addiction or drug abuse are at heightened risk of abusing Benadryl due to seeking drugs that produce a similar sedative effect as alcohol. This misuse of Benadryl can lead to addiction and a higher likelihood of overdose. It is essential to consult a healthcare provider and seek help if you or a loved one struggles with addiction or substance abuse.

Benadryl and Alcohol | FAQs

Are there serious side effects or risks of mixing Benadryl and Alcohol?

Yes, Benadryl and alcohol can cause serious side effects such as extreme drowsiness, dizziness, confusion, and impaired motor skills. This combination can increase the risk of accidents and, in severe cases, can lead to dangerous respiratory issues or heart problems.

When can I start drinking alcohol after taking Benadryl, Claritin, or Zyrtec?

It’s best to wait at least 24 hours after taking Benadryl before consuming alcohol. For Claritin or Zyrtec, waiting several hours is usually safe, but it’s important to check how the medication affects you before drinking. Always consult a healthcare professional for specific advice.

Can you take Benadryl after drinking?

It is not recommended to take Benadryl after drinking alcohol, as both substances can cause drowsiness, dizziness, and impaired coordination. Combining them may intensify these effects, increasing the risk of accidents or dangerous sedation. Always consult a healthcare professional before mixing alcohol and medications like Benadryl.

How long does Claritin stay in your system?

Claritin typically stays in your system for about 24 hours, as its effects last for a full day. However, traces of the drug may remain in your body for a few days, depending on factors like metabolism and overall health. Always follow dosing instructions and consult a healthcare professional if you’re unsure.

Can you drink on allergy meds?

It’s generally not recommended to drink alcohol while taking allergy medications like Benadryl, Claritin, or Zyrtec. Alcohol can intensify side effects such as drowsiness, dizziness, and impaired coordination. The combination may increase the risk of accidents or reduce the effectiveness of the medication. Always consult your doctor before mixing alcohol with allergy meds.

How much alcohol can you drink with Benadryl?

It’s best to avoid drinking alcohol entirely while taking Benadryl for allergy symptoms. Even small amounts of alcohol can amplify side effects like extreme drowsiness, dizziness, and impaired judgment. Combining the two may lead to serious risks, so it’s safest to abstain from alcohol while Benadryl is in your system.

Can I use alcohol with Benadryl as a sleep aid?

No, it’s not safe to use alcohol and Benadryl together as sleep aids. This is a dangerous combination since they are both depressants and can lead to serious health risks.

Get Treatment for Drug & Alcohol Addiction at Gratitude Lodge

If you’re wondering, “Can I take Benadryl with alcohol?”, it should now be clear that drinking with Benadryl is potentially dangerous. Maybe you are ready to address issues of alcohol abuse but unsure where to turn. We can help you combat alcohol use disorder here at Gratitude Lodge in Southern California, beginning with a supervised medical detox.

After a week or so, you will be ready to transition into one of the following treatment programs at rehab centers in Long Beach and Newport Beach, CA:

  • 30-day inpatient program
  • Dual diagnosis treatment program (for alcohol addictions with co-occurring mental health conditions)

All treatment programs for alcohol and Benadryl side effects at Gratitude Lodge combine evidence-based treatments and holistic therapies, including:

  • Psychotherapy
  • Medication-assisted treatment
  • Group therapy
  • Individual counseling
  • Family therapy
  • Holistic therapies (yoga, mindfulness, meditation)

To kickstart your recovery from alcohol addiction, call admissions today at 844-576-0144.

Sources

[1] https://www.drugs.com/benadryl.html

[2] https://www.webmd.com/drugs/2/drug-1428/diphenhydramine-oral/details

[3] https://go.drugbank.com/categories/DBCAT000399

[4] https://www.verywellhealth.com/benadryl-medication-information-83082#:~:text=Benadryl%20(diphenhydramine)%20is%20an%20effective,causes%20dry%20mouth%20and%20eyes.

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Jenni Bussi

Jenni Busse MS, LPCC

Jenni Busse MS, LPSS is the Clinical Director at Gratitude Lodge. Jenni oversees the clinical program and the clinical team at Gratitude Lodge as a whole. Jenni has worked in treatment for almost 14 years. Her background as a licensed therapist and her passion for helping others intersected with addiction recovery when she started working primarily in detox residential treatment.
Joe Gilmore

Joseph Gilmore

Joseph Gilmore has been working in the addiction industry for half a decade and has been writing about addiction and substance abuse treatment during that time. He has experience working for facilities all across the country. Connect with Joe on LinkedIn.

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