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Mixing Trazodone and Alcohol
Mixing trazodone and alcohol can have serious and potentially life-threatening consequences. If either alcohol or trazodone are consumed in excessive amounts, the interaction between these substances can intensify the effects of intoxication, leading to extreme drowsiness and increasing the risk of overdose and death.
Beyond this, long-term use of either alcohol (a commonly abused addictive substance) or trazodone (an FDA-approved tetracyclic antidepressant) can trigger physical dependence and the presentation of withdrawal symptoms upon discontinuation.
Today, you will discover:
- Can you mix trazodone and alcohol?
- What are the effects of trazodone and alcohol?
- What are the most common trazodone and alcohol interactions?
- What happens if you mix trazodone and alcohol?
- How can you connect with treatment for trazodone & alcohol abuse in Southern California?

Trazodone and Alcohol Interaction
The interaction between alcohol and trazodone can intensify the effects of both substances and lead to adverse reactions. Trazodone is a central nervous system depressant that affects certain neurotransmitters in the brain, while alcohol is also a CNS depressant that can further dampen the central nervous system. When combined, these substances can cause excessive sedation, drowsiness, and impaired motor function.



Side Effects of Trazodone and Alcohol
Mixing trazodone and alcohol can significantly amplify the side effects associated with each substance. An awareness of these potential side effects will help you understand the risks involved in combining trazodone with alcohol. These include:
Both trazodone and alcohol have sedative properties. Mixing alcohol and trazodone can lead to excessive sedation, causing extreme drowsiness and a profound feeling of fatigue. This can impair cognitive function, affect coordination, and increase the risk of accidents or falls.
Trazodone and alcohol can both impair judgment and coordination individually. When used together, these effects are magnified, making it dangerous to engage in activities such as driving or operating machinery.
Trazodone is primarily prescribed to manage depression. Alcohol, however, is a depressant and can worsen depressive symptoms. Combining trazodone and alcohol can lead to increased feelings of sadness, hopelessness, and may exacerbate the underlying depression.
Both trazodone and alcohol have the potential to depress the central nervous system, including the respiratory system. Combining them can further suppress breathing, leading to respiratory depression. This can be especially dangerous for those with pre-existing respiratory conditions, potentially leading to trazodone and alcohol death.
Trazodone and alcohol can independently affect heart function. Mixing them can lead to an irregular heartbeat, changes in blood pressure, and an increased risk of heart-related complications.
Trazodone alcohol can individually cause gastrointestinal issues such as nausea, vomiting, and stomach upset. When combined, these effects can be intensified, potentially leading to increased discomfort and digestive problems.
Individual experiences may vary, and the severity of these side effects can depend on factors
Individual reactions may vary, and the severity of side effects can be influenced by factors such as the dosage of trazodone, the amount of alcohol consumed, and individual tolerance levels. Avoid mixing trazodone and alcohol to minimize the potential for these adverse effects.
as the dosage of Prozac, the amount of alcohol consumed, and individual sensitivity. However, to minimize potential risks and ensure the most effective treatment, avoid the combination of Prozac and alcohol.

Trazodone & Alcohol Overdose
Combining trazodone and alcohol significantly increases the risk of an overdose, which can have severe consequences for your health.
- Trazodone overdose: Taking an excessive amount of trazodone can lead to an overdose. Symptoms of a trazodone overdose may include extreme drowsiness, confusion, rapid heartbeat, low blood pressure, seizures, and even loss of consciousness. An overdose of trazodone requires immediate medical attention.
- Alcohol overdose (alcohol poisoning): Consuming excessive amounts of alcohol can trigger alcohol poisoning, a condition that can be life-threatening. Common alcohol poisoning symptoms include confusion, vomiting, seizures, slow or irregular breathing, hypothermia, and unconsciousness. If you suspect someone has alcohol poisoning, seek emergency medical assistance immediately.
When trazodone and alcohol are mixed, the risk of both trazodone and alcohol overdose is heightened. The sedative effects of trazodone can mask the signs of alcohol intoxication, making it difficult to gauge the extent of alcohol consumption. This can increase the likelihood of unintentionally consuming excessive amounts of alcohol, leading to alcohol poisoning.
Prioritize your safety and well-being by avoiding the combination of trazodone and alcohol. If you or someone you know has mixed trazodone and alcohol and is experiencing severe symptoms or an overdose, call emergency services right away.
Remember: seeking medical attention promptly is vital in cases of overdose or suspected alcohol poisoning. If you have any concerns or questions regarding the use of trazodone or alcohol, consult with a healthcare professional who can provide you with the necessary guidance and support to ensure your health and safety.


Get Treatment for Alcohol Addiction at Gratitude Lodge
If you or someone you know is struggling with trazodone and alcohol addiction, Gratitude Lodge in Southern California is here to assist you on the path to recovery. Our pet-friendly rehabs in Newport Beach and Long Beach, CA, are designed to address both trazodone and alcohol addiction, in addition to mental health conditions.
Gratitude Lodge offers a supervised medical detox program that provides a safe and effective way to overcome trazodone and alcohol addiction and move towards ongoing recovery. Once detoxified, you can seamlessly transition into our comprehensive 30-day inpatient program, where you will receive specialized care and support.
Our treatment programs for trazodone and alcohol addiction integrate various evidence-based interventions, such as MAT (medication-assisted treatment), psychotherapy, group therapy, individual counseling, family therapy, holistic therapies, and aftercare support. We believe in a holistic and individualized approach to help individuals overcome their dual addiction and achieve lasting recovery.
To make the transition from active trazodone and alcohol addiction to ongoing recovery, you can place your trust in Gratitude Lodge. For admissions and further information, please contact us at 888-861-1658.
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